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腹部CT中的口服对比剂。一项双盲随机研究,比较泛影酸盐水溶液、碘海醇水溶液和碘海醇粘性溶液。

Oral contrast media in CT of the abdomen. A double-blind randomized study comparing an aqueous solution of amidotrizoate, an aqueous solution of iohexol and a viscous solution of iohexol.

作者信息

Lönnemark M, Magnusson A, Ahlström H

机构信息

Department of Diagnostic Radiology, Uppsala University, Sweden.

出版信息

Acta Radiol. 1993 Sep;34(5):517-9.

PMID:8369192
Abstract

In a double-blind randomized study 3 different preparations of oral contrast media for bowel opacification at CT of the abdomen have been compared. Plain aqueous solutions of amidotrizoate (9 mg I/ml) and iohexol (9 mg I/ml) were used as well as a preparation of iohexol (9 mg I/ml) to which a viscosity-increasing agent had been added. The distribution of the contrast media in the intestine, transit time and patient tolerance were evaluated. No significant differences were found regarding the distribution between the 3 preparations of contrast media, while there was a tendency for the transit time to be increased when the viscous preparation of iohexol was used. The aqueous solution of iohexol had the best taste, while the viscous preparation was markedly more difficult to drink. Aqueous solutions of iohexol and amidotrizoate were equal for bowel opacification and the addition of the viscosity-increasing agent did not improve the distribution of the contrast medium in the intestine.

摘要

在一项双盲随机研究中,对用于腹部CT肠道造影的3种不同口服造影剂制剂进行了比较。使用了泛影酸盐(9mg碘/ml)和碘海醇(9mg碘/ml)的普通水溶液,以及添加了增稠剂的碘海醇(9mg碘/ml)制剂。评估了造影剂在肠道中的分布、通过时间和患者耐受性。在3种造影剂制剂的分布方面未发现显著差异,而使用粘性碘海醇制剂时通过时间有增加的趋势。碘海醇水溶液口感最佳,而粘性制剂明显更难饮用。碘海醇和泛影酸盐的水溶液在肠道造影方面效果相当,添加增稠剂并未改善造影剂在肠道中的分布。

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