Roux Agnès, Payne Shelley M, Gilmore Michael S
Schepens Eye Research Institute, Boston, MA 02114, USA.
Cell Host Microbe. 2009 Aug 20;6(2):115-24. doi: 10.1016/j.chom.2009.07.004.
Bacterial-sensing circuits may be triggered by molecules originating from the environment (e.g., nutrients and chemoattractants). Bacteria also actively probe the environment for information by releasing molecular probes to measure conditions beyond the cell surface: a process known as telesensing. Perceiving the environment beyond is achieved by sensing environmentally induced changes in those probes, as occurs when a siderophore chelates an iron atom or a quorum-sensing signal is inactivated by a specific enzyme or adsorbent. This information, captured by chemical and physical changes induced in specifically produced molecules transiting through the environment, enables bacteria to mount a contextually appropriate response.
细菌感应回路可能由源自环境的分子（如营养物质和化学引诱剂）触发。细菌还通过释放分子探针来主动探测环境以获取信息，从而测量细胞表面之外的状况：这一过程称为遥测。感知细胞表面之外的环境是通过感应这些探针中由环境引起的变化来实现的，比如当一种铁载体螯合一个铁原子，或者一种群体感应信号被一种特定酶或吸附剂失活时。通过在环境中穿梭的特定产生的分子中诱导的化学和物理变化所捕获的这些信息，使细菌能够做出符合具体情况的适当反应。
