Systems Engineering and Computer Science Program, COPPE, Federal University of Rio de Janeiro, Caixa Postal 68511, 21941-972 Rio de Janeiro-RJ, Brazil.
Bioinformatics. 2009 Oct 15;25(20):2734-6. doi: 10.1093/bioinformatics/btp489. Epub 2009 Aug 14.
YADA can deisotope and decharge high-resolution mass spectra from large peptide molecules, link the precursor monoisotopic peak information to the corresponding tandem mass spectrum, and account for different co-fragmenting ion species (multiplexed spectra). We describe how YADA enables a pipeline consisting of ProLuCID and DTASelect for analyzing large-scale middle-down proteomics data.
YADA 可以对大肽分子进行去同位素和去电荷,将前体单同位素峰信息与相应的串联质谱联系起来,并解释不同的共碎裂离子种类(多路谱)。我们描述了 YADA 如何支持由 ProLuCID 和 DTASelect 组成的管道,用于分析大规模的中间向下蛋白质组学数据。