Department of Ophthalmology, Gachon University Gil Medical Center, Incheon, Korea.
Ophthalmologica. 2010;224(1):42-6. doi: 10.1159/000234907. Epub 2009 Aug 13.
To compare posterior capsular opacification (PCO) between a combined procedure and a sequential procedure of pars plana vitrectomy (PPV) and cataract surgery (CS).
The medical records of 89 eyes of 85 patients who underwent PPV and CS were retrospectively reviewed. There were 56 eyes of 52 patients with a combined PPV and CS (the combined surgery group), and 33 eyes of 33 patients with CS in a previously vitrectomized eye (the sequential surgery group). The control group was comprised of 130 eyes of 102 patients who underwent CS alone. All patients were followed up for at least 1 year after CS. The major outcome measures were the PCO rate and the interval between CS and PCO formation. There were no significant differences in age and the incidence of diabetes among the 3 groups.
The PCO rate checked at 1 year after CS was 12.5% (7/56) in the combined surgery group, 24.2% (8/33) in the sequential surgery group, and 4.6% (6/130) in the control group. The differences in the PCO rate between the subgroups as well as among the 3 groups were statistically significant (p < 0.05). There were no significant differences in the interval between CS and PCO formation among the 3 groups.
This study demonstrates that the PCO rate may be lower in patients who have a combined procedure of PPV and CS than in those who have a sequential procedure.
比较经平坦部玻璃体切除术（PPV）和白内障手术（CS）联合与序贯手术治疗后后囊膜混浊（PCO）的情况。
回顾性分析 85 例 89 眼接受 PPV 和 CS 的患者的病历。其中 56 眼 52 例患者行联合 PPV 和 CS（联合手术组），33 眼 33 例患者曾行玻璃体切割术的眼行 CS（序贯手术组），130 眼 102 例患者单纯行 CS（对照组）。所有患者 CS 后至少随访 1 年。主要观察指标为 PCO 发生率和 CS 与 PCO 形成之间的间隔。3 组患者的年龄和糖尿病发生率差异均无统计学意义。
CS 后 1 年时 PCO 发生率，联合手术组为 12.5%（7/56），序贯手术组为 24.2%（8/33），对照组为 4.6%（6/130）。各组间及组间 PCO 发生率差异均有统计学意义（p < 0.05）。3 组间 CS 与 PCO 形成之间的间隔差异无统计学意义。
本研究表明，与序贯手术相比，PPV 和 CS 联合手术患者的 PCO 发生率可能更低。
