Aldebot Stephanie, de Mamani Amy G Weisman
Department of Psychology, University of Miami, Coral Gables, FL 33124, USA.
J Nerv Ment Dis. 2009 Aug;197(8):580-4. doi: 10.1097/NMD.0b013e3181b05fbe.
Antipsychotics are often the first line of treatment for individuals with schizophrenia (). One challenge to effective treatment is lack of adherence to prescribed medication. Lower rates of adherence are associated with considerably higher rates of relapse and poorer course of illness. Therefore studying the characteristics that may be related to medication adherence is important. Coping styles may be one such factor. Individuals use a variety of coping mechanisms to manage and navigate difficult life events, including mental illness (). In the present study, 40 individuals with schizophrenia were assessed regarding their coping styles and medication adherence practices. As hypothesized, it was found that denial coping was inversely related to medication adherence. However, contrary to expectations, acceptance coping was not related to medication adherence. These findings suggest that targeting denial coping strategies in treatment may help foster more optimal strategies for managing schizophrenia.
抗精神病药物通常是精神分裂症患者的一线治疗药物。有效治疗面临的一个挑战是患者对医嘱用药的依从性差。依从率较低与复发率显著升高及病情转归较差相关。因此，研究可能与药物依从性相关的特征很重要。应对方式可能是其中一个因素。个体运用多种应对机制来处理和应对困难的生活事件，包括精神疾病。在本研究中，对40名精神分裂症患者的应对方式和药物依从性做法进行了评估。正如所假设的，发现否认应对与药物依从性呈负相关。然而，与预期相反，接受应对与药物依从性无关。这些发现表明，在治疗中针对否认应对策略可能有助于培养更优化的精神分裂症管理策略。
