Department of Chemistry, Rice University, P.O. Box 1892, Houston, Texas 77251-1892, USA.
Analyst. 2009 Sep;134(9):1745-50. doi: 10.1039/b909080k. Epub 2009 Jul 24.
Nanoshells are optically tunable core-shell nanostructures with demonstrated uses in surface enhanced spectroscopies. Based on their ability to support surface plasmons, which give rise to strongly enhanced electromagnetic fields at their surface, nanoshells provide simple, scalable, high-quality substrates. In this article, we outline the development and use of nanoshell-based substrates for direct, spectroscopic detection of biomolecules. Recent advances in the use of these nanostructures lead to improved spectroscopic quality, selectivity, and reproducibility.
纳米壳是一种光学可调谐的核壳纳米结构，已被证明在表面增强光谱学中有应用。基于它们支持表面等离激元的能力，这在其表面产生强烈增强的电磁场，纳米壳提供了简单、可扩展、高质量的衬底。在本文中，我们概述了基于纳米壳的衬底的开发和使用，用于生物分子的直接光谱检测。这些纳米结构的最新进展导致了光谱质量、选择性和重现性的提高。
