Bon Secours Hospital, Glasnevin, Dublin, Ireland.
Ir J Med Sci. 2009 Dec;178(4):397-400. doi: 10.1007/s11845-009-0404-7.
Cholelithiasis typically presents with right upper quadrant pain, as can pain from other right upper quadrant organs. Pain of cholelithiasis is often referred to tip of scapula. Professor Paddy Collins drew attention to fact that patients with gallstone pain would attempt to demonstrate this by placing their hand behind the back and thumb pointing upwards. This became known amongst his students as Collins' sign.
To evaluate accuracy of Collins' sign as indicator of cholelithiasis.
Case-control study performed on 202 patients with symptomatic cholelithiasis and 200 control patients (with oesophagitis, gastritis or duodenal ulcer). Questionnaire examined pain pattern in both groups. The results analysed using t test and χ(2) test.
Collins' sign was positive in 51.5% of gallstone patients and 7.5% of control group (P < 0.001).
Collins' sign was positive in over half of all patients with cholelithiasis and was useful discriminator in diagnosis of gallstones.
胆石症通常表现为右上腹疼痛，其他右上腹器官也会出现疼痛。胆石症的疼痛常常放射到肩胛尖端。Paddy Collins 教授注意到这样一个事实，即患有胆石症的患者会试图通过将手放在背后并将拇指向上指向来证明这一点。这在他的学生中被称为 Collins 征。
评估 Collins 征作为胆石症指标的准确性。
对 202 例有症状胆石症患者和 200 例对照组患者（食管炎、胃炎或十二指肠溃疡）进行病例对照研究。问卷调查了两组患者的疼痛模式。使用 t 检验和 χ(2)检验分析结果。
胆石症患者中 Collins 征阳性者占 51.5%，对照组阳性者占 7.5%（P < 0.001）。
Collins 征在半数以上的胆石症患者中为阳性，对胆石症的诊断具有重要的鉴别诊断价值。
