Schumann Barbara, Lebzien Peter, Ueberschär Karl-Heinz, Dänicke Sven
Institute of Animal Nutrition, Friedrich-Loeffler-Institute, Federal Research Institute for Animal Health, Braunschweig, Germany.
Mol Nutr Food Res. 2009 Jul;53(7):931-8. doi: 10.1002/mnfr.200800319.
The aim of the present study was to examine the effects of ergot contaminated concentrate at differing levels of feed intake on ergot alkaloid metabolism and carry over into milk. Twelve double fistulated (in the rumen and the proximal duodenum) Holstein Friesian cows were fed either the control diet (on a dry matter (DM) base: 60% maize silage, 40% concentrate) or the contaminated diet (concentrate contained 2.25% ergot, which caused an alkaloid concentration of the daily ration between 504.9 and 619.5 microg/kg DM) over a period of 4 weeks. Daily feed amounts were adjusted to the current performance which resulted in a dry matter intake (DMI) variation between 6.0 and 18.5 kg/day. The actual alkaloid exposure varied between 4.1 and 16.3 microg/kg body weight when the ergot contaminated concentrate was fed. Approximately 67% of the alkaloids fed were recovered in the duodenal ingesta, and approximately 24% were excreted with the faeces. No alkaloid residues could be detected in the blood or milk samples.
本研究的目的是检验不同采食量下，受麦角污染的精饲料对麦角生物碱代谢及在牛奶中的残留影响。选用12头安装了双瘘管（瘤胃和十二指肠近端）的荷斯坦奶牛，在4周的时间内，分别给它们饲喂对照日粮（以干物质计：60%玉米青贮料，40%精饲料）或受污染日粮（精饲料含有2.25%麦角，使得日粮中生物碱浓度在504.9至619.5微克/千克干物质之间）。每天的饲料量根据当前产奶量进行调整，干物质采食量（DMI）在6.0至18.5千克/天之间变化。饲喂受麦角污染的精饲料时，实际生物碱摄入量在4.1至16.3微克/千克体重之间变化。所饲喂生物碱中约67%在十二指肠食糜中回收，约24%随粪便排出。血液和牛奶样本中未检测到生物碱残留。
