Frisina Robert D
Otolaryngology Department, University of Rochester School of Medicine & Dentistry, Rochester, New York 14642-8629, USA.
Ann N Y Acad Sci. 2009 Jul;1170:708-17. doi: 10.1111/j.1749-6632.2009.03931.x.
Loss of sensory function in the aged has serious consequences for economic productivity, quality of life, and healthcare costs in the billions each year. Understanding the neural and molecular bases will pave the way for biomedical interventions to prevent, slow, or reverse these conditions. This chapter summarizes new information regarding age changes in the auditory system involving both the ear (peripheral) and brain (central). A goal is to provide findings that have implications for understanding some common biological underpinnings that affect sensory systems, providing a basis for eventual interventions to improve overall sensory functioning, including the chemical senses.
老年人感觉功能丧失对经济生产力、生活质量以及每年高达数十亿美元的医疗成本都有严重影响。了解其神经和分子基础将为预防、减缓或逆转这些状况的生物医学干预铺平道路。本章总结了有关听觉系统年龄变化的新信息,涉及耳朵(外周)和大脑(中枢)。目标是提供一些研究结果,这些结果有助于理解影响感觉系统的一些常见生物学基础,为最终改善整体感觉功能(包括化学感觉)的干预措施提供依据。