Providence St Vincent's Medical Center, Portland, Oregon 97225, USA.
Am J Crit Care. 2010 Jul;19(4):365-72. doi: 10.4037/ajcc2009255. Epub 2009 Aug 17.
Few data are available on the accuracy of thermodilution measurements of cardiac index with room-temperature injectates and a closed delivery system in patients with low cardiac indexes and/or hypothermic body temperatures.
To compare iced and room-temperature injectates for thermodilution measurement of cardiac index in postoperative cardiac surgical patients during hypothermia and normothermia.
In a convenience sample of cardiac surgical patients in a cardiac recovery unit, cardiac index was measured with both room-temperature and iced injectates during hypothermia (< or =36.0 degrees C) and normothermia (> or =36.1 degrees C and < or =38.0 degrees C). Device bias and precision were calculated and graphed by using the Bland-Altman method. A Student t test was used to determine differences between cardiac indexes by injectate temperature.
A total of 38 patients were studied. Mean bias and precision for room-temperature and iced injectates in all patients were 0.11 (SD, 0.27) during hypothermia and -0.03 (SD, 0.21) during normothermia. In hypothermic patients, cardiac index differed significantly between room-temperature and iced injectates (t(1,37) = 2.41, P = .02). Cardiac index measurements did not differ between room-temperature and iced injectates in normothermic patients (P = .33).
Although significant differences in thermodilution cardiac index were found between room-temperature and iced injectates during hypothermic body temperatures, these differences were small (mean, <0.11). These findings add to the results of the few studies on accuracy of room-temperature injectates for thermodilution measurement of cardiac index.
在低心指数和/或低体温患者中,使用室温注射剂和封闭输送系统进行热稀释心指数测量的准确性数据很少。
比较冰盐水和室温注射剂在心外科术后低体温和正常体温患者中进行热稀释心指数测量的效果。
在心脏复苏病房的心脏外科患者的方便样本中,在低体温(≤36.0°C)和正常体温(>36.1°C 且 <38.0°C)期间,使用室温和冰盐水注射剂测量心指数。使用 Bland-Altman 法计算和绘制设备偏差和精度,并使用学生 t 检验确定两种注射剂温度下心指数的差异。
共 38 例患者接受了研究。在所有患者中,室温和冰盐水注射剂的平均偏差和精度在低体温时分别为 0.11(SD,0.27)和 0.03(SD,0.21)。在低体温患者中,室温和冰盐水注射剂的心指数差异有统计学意义(t(1,37)=2.41,P=0.02)。在正常体温患者中,室温和冰盐水注射剂的心指数测量值无差异(P=0.33)。
尽管在低体温时室温和冰盐水注射剂之间的热稀释心指数存在显著差异,但这些差异很小(平均 <0.11)。这些发现增加了关于室温注射剂用于热稀释心指数测量的准确性的少数研究结果。