Yamamoto Yosuke, Kadota Masafumi, Nishimura Youichi
Department of Dermatology, Toyooka Hospital, Tobera, Toyooka, Hyogo, Japan.
Pediatr Dermatol. 2009 Jul-Aug;26(4):475-6. doi: 10.1111/j.1525-1470.2009.00959.x.
We present the case of a 9-month-old boy with yellow-brown papules that gradually increased in number over a period of 6 months without systemic involvement. Our case was clinicopathologically diagnosed as S-100-positive juvenile xanthogranuloma, and longitudinal observation revealed that strong S-100 reactivity disappeared in parallel with maturation of the lesions within 2 years after the initial diagnosis. These findings add to the complexity in cells of origin of this disorder.
我们报告一例9个月大的男童,其出现黄褐色丘疹,在6个月内数量逐渐增加,无全身受累。我们的病例经临床病理诊断为S-100阳性幼年性黄色肉芽肿,纵向观察显示,在初次诊断后2年内,随着病变成熟,强烈的S-100反应性消失。这些发现增加了这种疾病细胞起源的复杂性。