Institute of Head and Neck Studies and Education, University Hospital, Coventry, United Kingdom.
Head Neck. 2010 Mar;32(3):279-83. doi: 10.1002/hed.21175.
Review of the literature reveals considerable variability in the definitions and criteria used for reporting postoperative hypocalcemia. The lack of standardization prevents a meaningful comparison of results and performance locally with the national standard. It also prevents the pooling of data when performing meta-analysis, and may affect the comparison of research results.
A literature review was performed to identify the different definitions used to define hypocalcemia in post-thyroidectomy patients. We analyzed the incidence of hypocalcemia in the same cohort of 202 post thyroidectomy patients using these definitions.
The reported hypocalcemia rates varied from 0% to 46% for the same cohort depending on the definition of hypocalcemia used. Only one-third of biochemically hypocalcemic patients requested calcium supplementation.
This study demonstrates the need for more uniformity and standardization in the definitions used for reporting hypocalcemia rates.
文献回顾显示,术后低钙血症的定义和标准存在很大差异。缺乏标准化会妨碍对局部结果与国家标准进行有意义的比较,也妨碍进行荟萃分析时的数据汇总,并可能影响研究结果的比较。
进行文献回顾,以确定用于定义甲状腺切除术后患者低钙血症的不同定义。我们使用这些定义分析了同一组 202 例甲状腺切除术后患者的低钙血症发生率。
根据使用的低钙血症定义,同一队列的报告低钙血症发生率从 0%到 46%不等。只有三分之一的生化性低钙血症患者需要补钙。
本研究表明,需要在报告低钙血症发生率的定义中更加统一和标准化。