Vlahov D, Lee H, Taylor E, Canavaggio M, Canner C, Burczak J, Saah A J
Department of Epidemiology, Johns Hopkins School of Hygiene and Public Health, Baltimore, Maryland.
J Acquir Immune Defic Syndr (1988). 1990;3(5):531-5.
Serum specimens that had been obtained for routine operational procedures from consecutive entering male inmates during Spring 1987 and the same calendar period in 1988 were tested to identify prevalence and risk groups for antibody to HTLV-I/II. Specimens were assayed for antibody to HTLV-I/II using ELISA, RIPA, and Western blot techniques. Demographics were compared by serostatus using chi 2 and Fisher's exact tests. Of the 1,932 inmates entering prison, 49.3% were 25 years of age or older, 70.1% were black, 62.4% were committed from the Baltimore metropolitan area, 34.1% were intravenous drug users, and 7.0% demonstrated antibody to HIV-1. Among 1,932 inmates, 18 (0.9%) were HTLV-I/II seropositive. All seropositives were black; age greater than 25 years old was significantly (p less than 0.01) associated with seropositivity. Reactivity to HTLV-I/II did not vary significantly by year of entry, HIV-1 serostatus, jurisdiction, offense category, or sentence. Prevalence of HTLV-I/II among incoming male inmates was elevated compared to available local population comparisons. Additional blinded epidemiological serosurveys of antibody to HTLV-I/II are indicated for prison populations in order to monitor the extent and scope of infection in this population.
对1987年春季和1988年同一日历期间连续入狱的男性囚犯在常规操作程序中采集的血清样本进行检测，以确定HTLV-I/II抗体的流行率和风险群体。使用ELISA、RIPA和蛋白质印迹技术检测样本中的HTLV-I/II抗体。使用卡方检验和费舍尔精确检验按血清学状态比较人口统计学特征。在1932名入狱囚犯中，49.3%年龄在25岁及以上，70.1%为黑人，62.4%来自巴尔的摩大都市区，34.1%为静脉吸毒者，7.0%显示出HIV-1抗体。在1932名囚犯中，18人（0.9%）HTLV-I/II血清学呈阳性。所有血清学阳性者均为黑人；年龄大于25岁与血清学阳性显著相关（p<0.01）。对HTLV-I/II的反应性在入狱年份、HIV-1血清学状态、司法管辖区、犯罪类别或刑期方面没有显著差异。与当地可用的人群比较相比，入狱男性囚犯中HTLV-I/II的流行率有所升高。为了监测该人群中感染的程度和范围，建议对监狱人群进行额外的HTLV-I/II抗体盲法流行病学血清学调查。
