Universitair Ziekenhuis Brussel Kinderen, Laarbeeklaan 101, 1090 Brussels, Belgium.
Arch Dis Child. 2010 Jan;95(1):26-30. doi: 10.1136/adc.2008.156497. Epub 2009 Aug 20.
The aim of this preliminary study was to evaluate the efficacy of a 40 degrees supine body position on infant regurgitation, reflux-associated symptoms and acid reflux.
Thirty of 52 consecutive infants presenting with frequent regurgitation and reflux-associated symptoms occurring mainly during feeding were evaluated in the Multicare AR-Bed (Peos, Ninove, Belgium). The Infant-Gastroesophageal Reflux Questionnaire-Revised (I-GERQ-R) and an oesophageal pH monitoring were performed at inclusion and after 1 week.
Eight out of 30 (27%) infants did not tolerate the 40 degrees positioning, and had to be taken out of the study within the first 2 days. However, in 22/30 (73%) infants the I-GERQ-R and acid reflux decreased significantly with the Multicare AR-Bed. The mean duration of use of the Multicare AR-Bed was 3.2 months.
The results of this pilot study suggest that a specially made bed that nurses the infant at 40 degrees supine body position reduces regurgitation, acid reflux and reflux-associated symptoms. However, the intervention was open, the sample size small and the withdrawal rate was substantial. Larger trials are needed.
本初步研究旨在评估 40 度仰卧位对婴儿胃食管反流、反流相关症状和胃酸反流的疗效。
52 例频繁胃食管反流和反流相关症状的连续婴儿中,有 30 例(主要发生在喂养期间)在 Multicare AR-Bed(Peos,Ninove,比利时)接受评估。在纳入时和 1 周后进行婴儿胃食管反流问卷修订版(I-GERQ-R)和食管 pH 监测。
30 例中有 8 例(27%)婴儿不能耐受 40 度体位,在头 2 天内不得不退出研究。然而,在 22/30 例(73%)婴儿中,Multicare AR-Bed 显著降低了 I-GERQ-R 和胃酸反流。Multicare AR-Bed 的平均使用时间为 3.2 个月。
这项初步研究的结果表明,专门制作的让婴儿保持 40 度仰卧位的床可以减少胃食管反流、胃酸反流和反流相关症状。然而,该干预措施为开放性,样本量小,退出率高。需要更大规模的试验。