Willekens Inneke, Hoorens Anne, Geers Caroline, Op de Beeck Bart, Vandenbroucke Frederik, de Mey Johan
Department of Radiology, UZ Brussel, Laarbeeklaan 101, 1090 Brussels, Belgium.
World J Gastroenterol. 2009 Aug 21;15(31):3940-3. doi: 10.3748/wjg.15.3940.
Combined hepatocellular and cholangiocellular carcinoma (cHCC-CC) is a rare tumor type containing unequivocal elements of both hepatocellular carcinoma and cholangiocarcinoma that are intimately mixed. Although these tumors are usually considered to be more related to hepatocellular carcinoma than to cholangiocarcinoma, they sometimes, in contrast to hepatocellular carcinoma, contain a significant amount of fibrous stroma. This might in some cases explain atypical radiological features. We report a case of a cHCC-CC in a 47-year-old female that resembled focal nodular hyperplasia on Magnetic Resonance Imaging. Correlation of imaging and serum levels of alpha-fetoprotein and CA19.9 can help to make the correct diagnosis preoperatively.
肝内胆管癌合并肝细胞癌（cHCC-CC）是一种罕见的肿瘤类型，同时包含明确的肝细胞癌和胆管癌成分，且两者紧密混合。尽管这些肿瘤通常被认为与肝细胞癌的关系比与胆管癌的关系更为密切，但与肝细胞癌不同的是，它们有时含有大量纤维性间质。这在某些情况下可能解释了其非典型的放射学特征。我们报告一例47岁女性的cHCC-CC病例，该病例在磁共振成像上类似局灶性结节性增生。影像学检查与血清甲胎蛋白和CA19.9水平的相关性有助于术前做出正确诊断。
