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过去几十年日本结核分枝杆菌北京株的种群结构动态。

Population structure dynamics of Mycobacterium tuberculosis Beijing strains during past decades in Japan.

机构信息

Department of Microbiology, Kobe Institute of Health, Kobe, Japan.

出版信息

J Clin Microbiol. 2009 Oct;47(10):3340-3. doi: 10.1128/JCM.01061-09. Epub 2009 Aug 26.

Abstract

We used 909 strains to compare the population structures of the Mycobacterium tuberculosis Beijing family between different birth-year cohorts in Japan. The results revealed that the spread of a modern sublineage that has high transmissibility is currently increasing, while the spread of an ancient sublineage, STK, has significantly decreased in younger generations.

摘要

我们使用了 909 株菌株,比较了日本不同出生年份队列中结核分枝杆菌北京家族的种群结构。结果表明,具有高传染性的现代亚谱系的传播正在增加,而古老的 STK 亚谱系的传播在年轻一代中显著减少。

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