Mount Sinai Hospital Inflammatory Bowel Disease Group, Dr Zane Cohen Digestive Diseases Clinical Research Centre, University of Toronto, Toronto, Ontario, Canada.
Mol Diagn Ther. 2009;13(4):217-23. doi: 10.1007/BF03256328.
Technological advances in genomics and transcriptomics have resulted in the introduction of molecular tests into the clinical arena. Despite established uses of such tests in the oncology field, their integration into the management of complex diseases has not been widely evaluated. Progress in the field of inflammatory bowel disease (IBD) genetics has been rapid in recent years, and these advances have provided more urgent impetus to investigating the role of molecular tests in IBD. This article summarizes the current state of molecular testing available for IBD, and the potential utility of such tests as research in the area widens.
基因组学和转录组学的技术进步使得分子检测得以引入临床领域。尽管此类检测在肿瘤学领域的应用已经得到确立，但它们在复杂疾病管理中的整合尚未得到广泛评估。近年来，炎症性肠病 (IBD) 遗传学领域的进展迅速，这些进展为研究分子检测在 IBD 中的作用提供了更迫切的动力。本文总结了目前可用于 IBD 的分子检测方法，以及随着该领域研究的扩大，此类检测的潜在应用。
