Mustata Cristina, Torrens Marta, Pardo Ricardo, Pérez Clara, Farré Magi
Adicciones. 2009;21(3):181-6.
Some smokable herbal mixtures under the brand name Spice drugs have been sold on the Internet and in specialised shops (smart shops) since 2004. The mixtures are advertised as an exotic incense blend which releases a rich aroma and not for human consumption. When smoked, Spice drugs products have been reported by products have been reported by some users to have effects similar to those of cannabis. Spice drugs have received intensive attention in drug forums due to the possibility to obtain a non legal substitute of cannabis. Forensic analyses have found different potent synthetic cannabinoid agonists in some Spice drugs products, as JWH-018, CP 47497, JWH-073 and HU-210. There are few data about its pharmacological properties in animals, but nothing about its toxicity. At present, almost nothing is known about the pharmacology, toxicology and safety profile of such compounds in humans, except the opinions of consumers in internet forums. Neither the herbal ingredients of Spice drugs, nor any of the synthetic cannabinoids found in them, are internationally controlled under the 1961 or 1971 UN drug control conventions. Some European countries have recently taken legal actions to ban or otherwise control Spice drugs products and related compounds. These cannabinoid substances can be considered as new products to be added to the list of 'designer drugs'.
自2004年以来，一些打着“香料药物”品牌的可吸食草药混合物在互联网和专卖店（智能商店）出售。这些混合物被宣传为一种能释放浓郁香气的异国香薰混合物，并非供人食用。一些使用者报告称，吸食“香料药物”产品时会产生与大麻类似的效果。由于有可能获得大麻的非法替代品，“香料药物”在毒品论坛上受到了密切关注。法医分析在一些“香料药物”产品中发现了不同的强效合成大麻素激动剂，如JWH - 018、CP 47497、JWH - 073和HU - 210。关于其在动物体内的药理特性的数据很少，关于其毒性则一无所知。目前，除了互联网论坛上消费者的意见外，对于此类化合物在人体内的药理学、毒理学和安全性概况几乎一无所知。“香料药物”的草药成分及其所含的任何合成大麻素均未受到1961年或1971年联合国毒品管制公约的国际管制。一些欧洲国家最近已采取法律行动，禁止或以其他方式管制“香料药物”产品及相关化合物。这些大麻素物质可被视为有待添加到“设计药物”清单中的新产品。
