达哌唑使瞳孔散大逆转。
Reversal of mydriasis by dapiprazole.
作者信息
Allinson R W, Gerber D S, Bieber S, Hodes B L
机构信息
Department of Ophthalmology, University of Arizona, Tucson.
出版信息
Ann Ophthalmol. 1990 Apr;22(4):131-3, 138.
PMID:1972008
Abstract
The effect of topical dapiprazole, an alpha-adrenergic receptor blocker, in reversing mydriasis was studied in 50 subjects who received tropicamide 1% and phenylephrine 2.5%. There was a significant difference in the decrease in pupil size between the eye that received dapiprazole and the control eye. This study suggests that dapiprazole 0.5% eye drops are effective and safe in reversing mydriasis after instillation of tropicamide 1% and phenylephrine 2.5%.
摘要
在50名接受1%托吡卡胺和2.5%去氧肾上腺素的受试者中，研究了α-肾上腺素能受体阻滞剂局部用达哌拉唑对散瞳的逆转作用。接受达哌拉唑的眼睛与对照眼在瞳孔大小减小方面存在显著差异。本研究表明，0.5%达哌拉唑滴眼液在滴入1%托吡卡胺和2.5%去氧肾上腺素后逆转散瞳是有效且安全的。
相似文献
1
Reversal of mydriasis by dapiprazole.
Ann Ophthalmol. 1990 Apr;22(4):131-3, 138.
2
[Dapiprazol antagonizes tropicamide- and phenylephrine-induced mydriasis in the elderly].
Ophthalmologe. 1995 Apr;92(2):179-81.
3
Effects of dapiprazole on the reversal of pharmacologically induced mydriasis.
Optom Vis Sci. 1990 Sep;67(9):705-9. doi: 10.1097/00006324-199009000-00009.
4
The effect of dapiprazole on accommodative amplitude in eyes dilated with 0.5 percent tropicamide.
J Am Optom Assoc. 1993 Sep;64(9):625-8.
5
Efficacy of dapiprazole with hydroxyamphetamine hydrobromide and tropicamide.
J Am Optom Assoc. 1993 Sep;64(9):629-33.
6
Dapiprazole clinical efficiency for counteracting tropicamide 1%.
Optom Vis Sci. 1994 May;71(5):319-22. doi: 10.1097/00006324-199405000-00003.
7
[Driving ability after reversal of phenylephrine 10% induced mydriasis by dapiprazole 0.5%; a prospective study on 65 eyes].
Klin Monbl Augenheilkd. 2000 Dec;217(6):340-4. doi: 10.1055/s-2000-9572.
8
Effects of intraocular dapiprazole in the rabbit eye.
J Cataract Refract Surg. 1989 Nov;15(6):681-4. doi: 10.1016/s0886-3350(89)80037-9.
9
The additive miotic effects of dapiprazole and pilocarpine.
Graefes Arch Clin Exp Ophthalmol. 1995 Jul;233(7):448-51. doi: 10.1007/BF00180951.
10
Comparison of the effects on pupil size and accommodation of three regimens of topical dapiprazole.
Br J Ophthalmol. 1995 Jun;79(6):544-8. doi: 10.1136/bjo.79.6.544.
引用本文的文献
1
The Expanding Role of Pyridine and Dihydropyridine Scaffolds in Drug Design.
Drug Des Devel Ther. 2021 Oct 13;15:4289-4338. doi: 10.2147/DDDT.S329547. eCollection 2021.
2
Evaluation of alpha1-adrenoceptors in the rabbit iris: pharmacological characterization and expression of mRNA.
Br J Pharmacol. 1999 Jul;127(6):1367-74. doi: 10.1038/sj.bjp.0702675.
3
Comparison of the effects on pupil size and accommodation of three regimens of topical dapiprazole.
Br J Ophthalmol. 1995 Jun;79(6):544-8. doi: 10.1136/bjo.79.6.544.
4
The additive miotic effects of dapiprazole and pilocarpine.
Graefes Arch Clin Exp Ophthalmol. 1995 Jul;233(7):448-51. doi: 10.1007/BF00180951.
Zotero 插件