达哌唑使瞳孔散大逆转。
Reversal of mydriasis by dapiprazole.
作者信息
Allinson R W, Gerber D S, Bieber S, Hodes B L
机构信息
Department of Ophthalmology, University of Arizona, Tucson.
出版信息
Ann Ophthalmol. 1990 Apr;22(4):131-3, 138.
PMID:1972008
Abstract
The effect of topical dapiprazole, an alpha-adrenergic receptor blocker, in reversing mydriasis was studied in 50 subjects who received tropicamide 1% and phenylephrine 2.5%. There was a significant difference in the decrease in pupil size between the eye that received dapiprazole and the control eye. This study suggests that dapiprazole 0.5% eye drops are effective and safe in reversing mydriasis after instillation of tropicamide 1% and phenylephrine 2.5%.
摘要
在50名接受1%托吡卡胺和2.5%去氧肾上腺素的受试者中，研究了α-肾上腺素能受体阻滞剂局部用达哌拉唑对散瞳的逆转作用。接受达哌拉唑的眼睛与对照眼在瞳孔大小减小方面存在显著差异。本研究表明，0.5%达哌拉唑滴眼液在滴入1%托吡卡胺和2.5%去氧肾上腺素后逆转散瞳是有效且安全的。
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