Warlich M, Weik R, Höh H, Ruprecht K W
Augenklinik mit Poliklinik und Lehranstalt für Orthoptisten, Universität des Saarlandes, Homburg.
Ophthalmologe. 1995 Apr;92(2):179-81.
Dapiprazole eye drops were applied 1 h after topical tropicamide or phenylephrine instillation in 30 elderly subjects. Pupil diameter normalized much earlier than in controls receiving placebo. Dapiprazole constricted the tropicamide-dilated pupil by 1 mm after 1 h and normalized the pupil diameter of the phenylephrine-dilated pupil within 1 h, whereas the pupils of the patients receiving placebo remained dilated. Intraocular pressure did not change; no major side effects were seen.
在30名老年受试者中，在局部滴入托吡卡胺或去氧肾上腺素1小时后应用达哌拉唑滴眼液。瞳孔直径恢复正常的时间比接受安慰剂的对照组要早得多。达哌拉唑在1小时后使托吡卡胺散瞳的瞳孔缩小1毫米，并在1小时内使去氧肾上腺素散瞳的瞳孔直径恢复正常，而接受安慰剂的患者的瞳孔仍处于散瞳状态。眼压没有变化；未观察到重大副作用。
