足月妊娠尼日利亚妇女及其新生儿的血浆锌和铜水平

Plasma zinc and copper in pregnant Nigerian women at term and their newborn babies.

作者信息

Okonofua F E, Isinkaye A, Onwudiegwu U, Amole F A, Emofurieta W A, Ugwu N C

机构信息

Department of Obstetrics and Gynaecology, Obafemi Awolowo University, Ile-Ife, Nigeria.

出版信息

Int J Gynaecol Obstet. 1990 Jul;32(3):243-5. doi: 10.1016/0020-7292(90)90352-l.

DOI:10.1016/0020-7292(90)90352-l

PMID:1972116

Abstract

The concentration of copper and zinc was determined by atomic absorption spectrophotometry in 26 normal Nigerian women at term and their newborn babies. Cord zinc was significantly greater than maternal zinc. In contrast, cord copper was lower than maternal copper. There was only a weak correlation between cord copper and maternal copper but none between cord zinc and maternal zinc. There was no correlation between maternal and cord zinc and neonatal birthweight. However, an inverse correlation was found between maternal and cord copper and neonatal birthweight. These results indicate that: (1) zinc has no effect on fetal growth in Nigerian women but (2) copper may have a negative effect on fetal growth.

摘要

采用原子吸收分光光度法测定了26名足月尼日利亚正常妇女及其新生儿体内铜和锌的浓度。脐血锌含量显著高于母体锌含量。相比之下，脐血铜含量低于母体铜含量。脐血铜与母体铜之间仅有微弱的相关性，而脐血锌与母体锌之间无相关性。母体和脐血锌与新生儿出生体重之间无相关性。然而，发现母体和脐血铜与新生儿出生体重呈负相关。这些结果表明：（1）锌对尼日利亚妇女的胎儿生长没有影响，但（2）铜可能对胎儿生长有负面影响。