短柄五加茎皮中的三萜皂苷

Triterpenoid saponins from the stem bark of Acanthopanax brachypus HARMS.

作者信息

Hu Hao-Bin, Zheng Xu-Dong, Cao Hong, Guo Xiao-Qiang, Hu Huai-Sheng

机构信息

College of Chemistry and Chemical Engineering, Longdong University, China.

出版信息

Chem Pharm Bull (Tokyo). 2009 Sep;57(9):1000-3. doi: 10.1248/cpb.57.1000.

DOI:10.1248/cpb.57.1000

PMID:19721265

Abstract

Two new triterpenoid saponins, brachyposide A (1) {3-O-beta-D-galactopyranosyl-(1-->2)-[beta-D-xylopyranosyl-(1-->3)]-beta-D-glucuronopyranosyl-2beta,3beta,16alpha,23-tetrahydroxyolean-12-en-28-oic acid 28-O-beta-D-apiofuranosyl-(1-->3)-beta-D-xylopyranosyl-(1-->4)-alpha-L-rhamnopyranosyl-(1-->2)-alpha-L-arabinopyranosyl ester} and brachyposide B (2) {3-O-beta-D-glucopyranosyl-(1-->3)-beta-D-galactopyranosyl-(1-->3)-beta-D-glucuronopyranosyl-2beta,3beta,23-trihydroxyolean-12-en-28-oic acid 28-O-beta-D-xylopyranosyl-(1-->4)-[beta-D-apiofuranosyl-(1-->3)]-alpha-L-rhamnopyranosyl-(1-->2)-beta-D-glucopyranosyl ester}, together with four known triterpenoid saponins, including tabguticoside A, nipponoside D, palmatoside E and ciwujianoside A(1), were isolated from the stem bark of Acanthopanax brachypus. Their structures were elucidated on the basis of spectroscopic and chemical evidence.

摘要

从短梗五加茎皮中分离得到两个新的三萜皂苷，短梗皂苷A（1）{3-O-β-D-吡喃半乳糖基-（1→2）-[β-D-吡喃木糖基-（1→3）]-β-D-吡喃葡萄糖醛酸基-2β，3β，16α，23-四羟基齐墩果-12-烯-28-酸28-O-β-D-吡喃芹糖基-（1→3）-β-D-吡喃木糖基-（1→4）-α-L-吡喃鼠李糖基-（1→2）-α-L-吡喃阿拉伯糖基酯}和短梗皂苷B（2）{3-O-β-D-吡喃葡萄糖基-（1→3）-β-D-吡喃半乳糖基-（1→3）-β-D-吡喃葡萄糖醛酸基-2β，3β，23-三羟基齐墩果-12-烯-28-酸28-O-β-D-吡喃木糖基-（1→4）-[β-D-吡喃芹糖基-（1→3）]-α-L-吡喃鼠李糖基-（1→2）-β-D-吡喃葡萄糖基酯}，以及四个已知的三萜皂苷，包括刺五加苷A、日本皂苷D、掌叶皂苷E和刺五加苷A（1）。通过光谱和化学证据阐明了它们的结构。