Garcia Isabel, Tabak Lawrence A
National Institute of Dental and Craniofacial Research, National Institutes of Health, 31 Center Drive, Building 31, Room 2C39, Bethesda, MD 20892, USA.
J Am Dent Assoc. 2009 Sep;140 Suppl 1(Suppl 1):44S-48S. doi: 10.14219/jada.archive.2009.0357.
New tools are enabling researchers to understand the mysteries of oral biology and disease and to change profoundly the treatment of oral, dental and craniofacial diseases and disorders. The authors explore advances in modern science and technology and how they will change oral health care in the future.
Emerging technologies such as salivary diagnostics, high-resolution imaging and nanotechnologies, as well as other new tools will lead to efficient and highly effective personalized dental treatments. A new generation of cell-based therapies will be available for regenerating tissues, and anti-inflammatory drugs and pain medications will be tailored to maximize efficacy and safety. Large teams of clinicians and scientists will tackle increasingly complex problems, and advances in computational sciences will make it possible to create virtual teams across the world. Information technology systems will enable clinicians to examine and integrate information obtained from all databases in cyberspace.
As scientists discover newer and better methods to preempt and prevent disease, they must translate these methods into tools for people at greatest risk of developing disease. Conquering the array of complex diseases that affect the oral and craniofacial complex will require multifaceted strategies and multidisciplinary cooperation.
新工具使研究人员能够理解口腔生物学和疾病的奥秘，并深刻改变口腔、牙齿和颅面疾病及病症的治疗方法。作者探讨了现代科学技术的进展以及它们未来将如何改变口腔医疗保健。
诸如唾液诊断、高分辨率成像和纳米技术等新兴技术，以及其他新工具将带来高效且高度有效的个性化牙科治疗。新一代基于细胞的疗法将可用于组织再生，抗炎药物和止痛药物将进行定制以实现疗效和安全性的最大化。大批临床医生和科学家团队将应对日益复杂的问题，计算科学的进展将使在全球范围内创建虚拟团队成为可能。信息技术系统将使临床医生能够检查和整合从网络空间中所有数据库获取的信息。
随着科学家发现更新更好的疾病预防和预占方法，他们必须将这些方法转化为针对疾病发生风险最高人群的工具。攻克影响口腔和颅面复合体的一系列复杂疾病将需要多方面的策略和多学科合作。
