Dept. of TB and Chest Diseases, Kasturba Medical College, Attavar, Mangalore, Karnataka, India.
Ann Thorac Med. 2007 Jan;2(1):14-7. doi: 10.4103/1817-1737.30356.
Empyema thoracis is a disease that, despite centuries of study, still causes significant morbidity and mortality.
The present study was undertaken to study the age-sex profile, symptomatology, microbiologic findings, etiology and the management and treatment outcome in a tertiary care hospital.
A prospective study of empyema thoracis was conducted on 40 consecutive patients with empyema thoracis admitted to the tuberculosis and chest diseases ward of a teaching hospital.
The demographic data, clinical presentation, microbiological findings, etiology, the clinical course and management were recorded as per a planned pro forma and analyzed.
The peak age was in the range of 21-40 years, the male-to-female ratio was 3.4:1.0 and the left pleura was more commonly affected than the right pleura. Risk factors include pulmonary tuberculosis, chronic obstructive pulmonary diseases, smoking, diabetes mellitus and pneumonia. Etiology of empyema was tubercular in 65% cases and nontubercular in 35% cases. Gram-negative organisms were cultured in 11 cases (27.5%). Two patients received antibiotics with repeated thoracentesis only, intercostal chest tube drainage was required in 38 cases (95%) and more aggressive surgery was performed on 2 patients. The average duration for which the chest tube was kept in the complete expansion cases was 22.3 days.
It was concluded that all cases of simple empyema with thin pus and only those cases of simple empyema with thick pus where size of empyema is small should be managed by aspiration/s. Cases failed by the above method, all cases of simple empyema with thick pus and with moderate to large size of empyema and all cases of empyema with bronchopleural fistula should be managed by intercostal drainage tube connected to water seal. It was also observed that all cases of empyema complicated by bronchopleural fistula were difficult to manage and needed major surgery.
尽管经过了几个世纪的研究,脓胸仍然是一种导致严重发病率和死亡率的疾病。
本研究旨在研究三级保健医院中脓胸的年龄性别分布、症状、微生物学发现、病因以及治疗管理和治疗结果。
对一家教学医院的结核病和胸部疾病病房收治的 40 例连续脓胸患者进行了前瞻性研究。
按照预定的方案记录人口统计学数据、临床表现、微生物学发现、病因、临床过程和治疗,并进行分析。
发病高峰年龄在 21-40 岁之间,男女比例为 3.4:1.0,左侧胸膜较右侧胸膜更常受累。危险因素包括肺结核、慢性阻塞性肺疾病、吸烟、糖尿病和肺炎。脓胸的病因在 65%的病例中为结核性,在 35%的病例中为非结核性。11 例(27.5%)培养出革兰氏阴性菌。仅 2 例患者接受抗生素联合反复胸腔穿刺治疗,38 例(95%)需要肋间胸腔引流管引流,2 例患者接受更积极的手术治疗。完全扩张病例中胸腔引流管留置的平均时间为 22.3 天。
所有稀薄脓液的单纯性脓胸病例,以及仅脓液较厚但脓腔较小的单纯性脓胸病例,均应采用抽吸/引流治疗。对于上述方法无效的病例、所有脓液较厚且脓腔中等至较大的单纯性脓胸病例以及所有合并支气管胸膜瘘的脓胸病例,均应采用与水封连接的肋间引流管进行治疗。还观察到,所有合并支气管胸膜瘘的脓胸病例均难以治疗,需要进行重大手术。