Ashbaugh D G
Department of Surgery, University of Washington, Seattle 98195.
Chest. 1991 May;99(5):1162-5. doi: 10.1378/chest.99.5.1162.
The effects of delay in surgical treatment and the choice of operation on morbidity associated with empyema thoracis were evaluated in 122 consecutive patients. Patients (71 from a private practice and 51 from an inner-city trauma/indigent care facility) eligible for study were divided into treatment groups of chest tube only (CT = 39) and open drainage (OD = 19), or decortication (DC = 65). Delay in treatment was defined as greater than 3 days from recognition of empyema to CT and greater than 14 days to OD or DC when chest tubes were inadequate or were not used initially. Delay in OD significantly increased total illness (p = 0.023), days until removal of chest tubes (p = 0.037), and hospital stay (p = .048), but did not affect postoperative stay. Delay in DC increased total illness (p = 0.0001), but did not affect other variables. Delay in CT increased mortality from 3.4 percent to 16 percent. Delay did not increase mortality in OD and DC. DC was superior to OD in patients requiring major operation in total illness days (DC = 36.1 vs OD = 106.1) (p = 0.0005), days until removal of tubes (DC = 7.5 vs OD = 78.3) (p = 0.0001), and postoperative stay (DC = 11.6 vs OD = 17.3) (p = 0.018). Overall mortality was lowest in the DC group (6.1 percent). Delay in treatment increases morbidity and DC is more effective than OD in reducing morbidity and mortality when surgical intervention is necessary.
对122例连续性脓胸患者评估了手术治疗延迟及手术选择对发病率的影响。符合研究条件的患者(71例来自私人诊所,51例来自市中心创伤/贫困护理机构)被分为单纯胸管治疗组(CT = 39)、开放引流组(OD = 19)或胸膜剥脱术组(DC = 65)。治疗延迟定义为从确诊脓胸至行胸管治疗超过3天,若最初未置胸管或胸管引流不足,则至行开放引流或胸膜剥脱术超过14天。开放引流延迟显著增加了总病程(p = 0.023)、胸管拔除天数(p = 0.037)及住院时间(p = 0.048),但不影响术后住院时间。胸膜剥脱术延迟增加了总病程(p = 0.0001),但不影响其他变量。胸管治疗延迟使死亡率从3.4%升至16%。延迟未增加开放引流和胸膜剥脱术的死亡率。在需要进行大手术的患者中,胸膜剥脱术在总病程天数(胸膜剥脱术= 36.1天 vs 开放引流= 106.1天)(p = 0.0005)、胸管拔除天数(胸膜剥脱术= 7.5天 vs 开放引流= 78.3天)(p = 0.0001)及术后住院时间(胸膜剥脱术= 11.6天 vs 开放引流= 17.3天)(p = 0.018)方面优于开放引流。总体死亡率在胸膜剥脱术组最低(6.1%)。治疗延迟会增加发病率,当需要手术干预时,胸膜剥脱术在降低发病率和死亡率方面比开放引流更有效。