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恶劣心境障碍:被遗忘与忽视了吗?

Dysthymic disorder: forlorn and overlooked?

作者信息

Sansone Randy A, Sansone Lori A

机构信息

Dr. R. Sansone is a professor in the Departments of Psychiatry and Internal Medicine at Wright State University School of Medicine in Dayton, Ohio, and Director of Psychiatry Education at Kettering Medical Center in Kettering, Ohio.

出版信息

Psychiatry (Edgmont). 2009 May;6(5):46-51.

PMID:19724735
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2719439/
Abstract

This ongoing column is dedicated to the challenging clinical interface between psychiatry and primary care-two fields that are inexorably linked.Dysthymic disorder is a smoldering mood disturbance characterized by a long duration (at least two years in adults) as well as transient periods of normal mood. The disorder is fairly common in the US general population (3-6%) as well as in primary care (7%) and mental health settings (up to one-third of psychiatric outpatients). While the etiology of dysthymia remains unknown, there appears to be a genetic susceptibility, which may manifest in the presence of various psychosocial stressors. While the Diagnostic and Statistical Manual of Mental Disorders diagnostic criteria are fairly clear, the disorder can be easily under-recognized for a variety of reasons. Treatment may include pharmacotherapy and psychotherapy, although the overall treatment course is oftentimes characterized by protracted symptoms and relapses.

摘要

本连载专栏致力于探讨精神病学与初级保健这两个紧密相连领域之间具有挑战性的临床界面。恶劣心境障碍是一种隐匿的情绪紊乱,其特征为持续时间长(成年人至少两年)以及情绪正常的短暂时期。该障碍在美国普通人群中相当常见(3%-6%),在初级保健机构中也较为常见(7%),在心理健康机构中同样常见(高达三分之一的精神科门诊患者)。虽然恶劣心境障碍的病因尚不清楚,但似乎存在遗传易感性,这可能在各种心理社会应激源存在时显现出来。尽管《精神障碍诊断与统计手册》的诊断标准相当明确,但由于各种原因,该障碍很容易被漏诊。治疗可能包括药物治疗和心理治疗,不过总体治疗过程往往具有症状迁延和复发的特点。

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本文引用的文献

1
Early Onset Dysthymic Disorder in Children and Adolescents: Clinical Implications and Future Directions.儿童和青少年的早发性心境恶劣障碍:临床意义及未来方向
Child Adolesc Ment Health. 2002 May;7(2):79-84. doi: 10.1111/1475-3588.00015.
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Characteristics, recognition and treatment of dysthymics in primary care.基层医疗中心境恶劣患者的特征、识别与治疗。
Eur Psychiatry. 1998 Jul;13(4):198-202. doi: 10.1016/S0924-9338(98)80004-7.
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[One year prevalence of mental disorders comorbidity and associated socio-demographic risk factors in the general population of Spain. Results of the ESEMeD-Spain study].[西班牙普通人群中精神障碍共病的一年患病率及相关社会人口学风险因素。ESEMeD-西班牙研究结果]
Actas Esp Psiquiatr. 2007 Sep;35 Suppl 2:4-11.
4
Psychosocial impact of dysthymia: a study among married patients.心境恶劣障碍的社会心理影响:一项针对已婚患者的研究。
J Affect Disord. 2008 Jul;109(1-2):199-204. doi: 10.1016/j.jad.2007.11.006. Epub 2007 Dec 31.
5
Duloxetine treatment of dysthymia and double depression: an open-label trial.度洛西汀治疗恶劣心境障碍和双重抑郁:一项开放标签试验。
J Clin Psychiatry. 2007 May;68(5):761-5. doi: 10.4088/jcp.v68n0514.
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Dysthymic disorder and double depression: prediction of 10-year course trajectories and outcomes.恶劣心境障碍与双重抑郁:10年病程轨迹及转归的预测
J Psychiatr Res. 2008 Apr;42(5):408-15. doi: 10.1016/j.jpsychires.2007.01.009. Epub 2007 Apr 26.
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Epidemiology of subtypes of depression.抑郁症亚型的流行病学。
Acta Psychiatr Scand Suppl. 2007(433):85-9. doi: 10.1111/j.1600-0447.2007.00966.x.
8
Psychometric study of dysthymic patients and their first-degree relatives.恶劣心境障碍患者及其一级亲属的心理测量学研究。
J Egypt Public Health Assoc. 2001;76(1-2):89-105.
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Clinical factors associated with relapse in primary care patients with chronic or recurrent depression.与慢性或复发性抑郁症初级保健患者复发相关的临床因素。
J Affect Disord. 2007 Aug;101(1-3):57-63. doi: 10.1016/j.jad.2006.10.023. Epub 2006 Dec 6.
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Ten-year prospective follow-up study of the naturalistic course of dysthymic disorder and double depression.心境恶劣障碍和双重抑郁自然病程的十年前瞻性随访研究
Am J Psychiatry. 2006 May;163(5):872-80. doi: 10.1176/ajp.2006.163.5.872.