质子泵抑制剂与噻吩并吡啶类药物联用的风险：事实还是虚构？ - Suppr

Risk of combining PPIs with thienopyridines: fact or fiction?

作者信息

Sibbing Dirk, Kastrati Adnan

机构信息

Deutsches Herzzentrum München und 1 Medizinische Klinik rechts der Isar, Technische Universität München, 80636 Munich, Germany.

出版信息

Lancet. 2009 Sep 19;374(9694):952-954. doi: 10.1016/S0140-6736(09)61562-2. Epub 2009 Aug 31.

DOI:10.1016/S0140-6736(09)61562-2

PMID:19726077

Abstract

摘要

相似文献

Risk of combining PPIs with thienopyridines: fact or fiction?质子泵抑制剂与噻吩并吡啶类药物联用的风险：事实还是虚构？

Lancet. 2009 Sep 19;374(9694):952-954. doi: 10.1016/S0140-6736(09)61562-2. Epub 2009 Aug 31.

ACCF/ACG/AHA 2010 expert consensus document on the concomitant use of proton pump inhibitors and thienopyridines: a focused update of the ACCF/ACG/AHA 2008 expert consensus document on reducing the gastrointestinal risks of antiplatelet therapy and NSAID use.ACCF/ACG/AHA 2010质子泵抑制剂与噻吩吡啶类药物联合使用专家共识文件：ACCF/ACG/AHA 2008关于降低抗血小板治疗和使用非甾体抗炎药胃肠道风险的专家共识文件重点更新版

Am J Gastroenterol. 2010 Dec;105(12):2533-49. doi: 10.1038/ajg.2010.445.

ACCF/ACG/AHA 2010 Expert Consensus Document on the concomitant use of proton pump inhibitors and thienopyridines: a focused update of the ACCF/ACG/AHA 2008 expert consensus document on reducing the gastrointestinal risks of antiplatelet therapy and NSAID use: a report of the American College of Cardiology Foundation Task Force on Expert Consensus Documents.ACCF/ACG/AHA 2010质子泵抑制剂与噻吩并吡啶类药物联合使用专家共识文件：ACCF/ACG/AHA 2008关于降低抗血小板治疗和非甾体抗炎药使用胃肠道风险专家共识文件的重点更新：美国心脏病学会基金会专家共识文件特别工作组报告

Circulation. 2010 Dec 14;122(24):2619-33. doi: 10.1161/CIR.0b013e318202f701. Epub 2010 Nov 8.

Pharmacodynamic effect and clinical efficacy of clopidogrel and prasugrel with or without a proton-pump inhibitor: an analysis of two randomised trials.氯吡格雷与普拉格雷联用或不联用质子泵抑制剂的药效学效应及临床疗效：两项随机试验的分析

Lancet. 2009 Sep 19;374(9694):989-997. doi: 10.1016/S0140-6736(09)61525-7. Epub 2009 Aug 31.

A possible mechanism for the differences in efficiency and variability of active metabolite formation from thienopyridine antiplatelet agents, prasugrel and clopidogrel.噻吩并吡啶类抗血小板药物（普拉格雷和氯吡格雷）活性代谢产物形成的效率和变异性差异的可能机制。

Drug Metab Dispos. 2009 Nov;37(11):2145-52. doi: 10.1124/dmd.109.028498. Epub 2009 Aug 24.

Proton pump inhibitor and clopidogrel interaction: fact or fiction?质子泵抑制剂与氯吡格雷相互作用：事实还是虚构？

Am J Gastroenterol. 2010 Jan;105(1):34-41. doi: 10.1038/ajg.2009.638. Epub 2009 Nov 10.

Dissecting the activation of thienopyridines by cytochromes P450 using a pharmacodynamic assay in vitro.用体外药效测定法剖析细胞色素 P450 对噻吩并吡啶类化合物的激活作用。

J Pharmacol Exp Ther. 2011 Nov;339(2):589-96. doi: 10.1124/jpet.111.184895. Epub 2011 Aug 9.

[Clopidogrel and proton pump inhibitors: insufficient evidence of interaction].[氯吡格雷与质子泵抑制剂：相互作用证据不足]

Ned Tijdschr Geneeskd. 2011;155(28):A2404.

[Interaction between clopidogrel and proton pump inhibitors].[氯吡格雷与质子泵抑制剂之间的相互作用]

Ned Tijdschr Geneeskd. 2011;155(28):A2442.

Metabolism and disposition of the thienopyridine antiplatelet drugs ticlopidine, clopidogrel, and prasugrel in humans.在人类中噻吩吡啶类抗血小板药物替卡格雷、氯吡格雷和普拉格雷的代谢和处置。

J Clin Pharmacol. 2010 Feb;50(2):126-42. doi: 10.1177/0091270009343005. Epub 2009 Nov 30.

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CYP2C19*2/ABCB1-C3435T polymorphism and risk of cardiovascular events in coronary artery disease patients on clopidogrel: is clinical testing helpful?CYP2C19*2/ABCB1-C3435T基因多态性与接受氯吡格雷治疗的冠心病患者发生心血管事件的风险：临床检测是否有帮助？

Indian Heart J. 2012 Jul-Aug;64(4):341-52. doi: 10.1016/j.ihj.2012.06.003. Epub 2012 Jun 21.

How Should Patients Requiring Dual Antiplatelet Therapy be Managed When Undergoing Elective Endoscopic Gastrointestinal Procedures?接受择期内镜胃肠道手术的双联抗血小板治疗患者应如何管理？

Curr Treat Options Cardiovasc Med. 2011 Feb;13(1):46-56. doi: 10.1007/s11936-010-0107-4.

Safety of proton pump inhibitors: current evidence for osteoporosis and interaction with antiplatelet agents.质子泵抑制剂的安全性：关于骨质疏松症及与抗血小板药物相互作用的当前证据

Curr Gastroenterol Rep. 2010 Jun;12(3):167-74. doi: 10.1007/s11894-010-0103-6.

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Risk of combining PPIs with thienopyridines: fact or fiction?

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