Department of Gastrointestinal Sciences, Christian Medical College, Vellore, Tamil Nadu 632004, India.
Trans R Soc Trop Med Hyg. 2010 Apr;104(4):307-8. doi: 10.1016/j.trstmh.2009.07.017. Epub 2009 Sep 2.
Hepatitis E virus (HEV) is an important cause of sporadic and epidemic hepatitis E infection in northern India. Sera, collected from different age groups in rural (n=1144) and urban (n=1135) areas using a probability proportional to size survey, were tested using an ELISA for IgG antibodies. Antibodies increased with age in both populations, but the urban population had higher exposure in all age groups (Mann-Whitney U test, P<0.001 for all age groups except children <5 years). These results indicate that urban populations with higher density and common water supplies may be at greater risk of hepatitis E.
戊型肝炎病毒 (HEV) 是印度北部散发和流行戊型肝炎感染的重要原因。采用与规模成正比的概率抽样方法，从农村（n=1144）和城市（n=1135）地区的不同年龄组采集血清，使用 ELISA 检测 IgG 抗体。两种人群的抗体均随年龄增长而增加，但城市人群在所有年龄组的暴露率均较高（Mann-Whitney U 检验，除 5 岁以下儿童外，所有年龄组 P<0.001）。这些结果表明，人口密度较高且共用供水的城市人群可能面临更大的戊型肝炎风险。
