Donor Sibling Registry, PO Box 1571, Nederland, CO, USA.
Hum Reprod. 2009 Dec;24(12):3144-9. doi: 10.1093/humrep/dep309. Epub 2009 Sep 3.
First-person reports of oocyte donors, years after their donation, can give valuable information about medical complications of oocyte donation, as well as changes potentially required in procedures and priorities of US-based in vitro fertilization (IVF) centers. This paper reports findings from an online survey of former oocyte donors.
The instrument was an author-constructed questionnaire completed online on the Donor Sibling Registry website. Questions assessed women's accounts of medical complications, contact with the infertility clinic through which they had provided ova, and information exchange or contact with people conceived from their ova.
Responses were received from 49.1% of the 287 donors with valid e-mail addresses. The 155 respondents completed the survey an average of 9.4 years after their first donation. Reported medical complications included ovarian hypersensitivity syndrome (30.3%) and infertility (9.6%). Subsequent to ova donation, 2.6% of women reported that they had been contacted by the IVF clinic for medical updates. On the questionnaire, 34.2% of women reported that medical changes they thought would interest donor children; half said that they had attempted to report these changes to the clinic with variable results. Many, who did not report such information, did not realize they could or should. Donors said that they frequently had not sought information about pregnancy outcomes because of confusion about the definition of 'anonymity' or 'confidentiality'.
US-based IVF clinics need to give clearer guidelines to anonymous oocyte donors about follow-up information exchange. Additional long-term studies are needed to ascertain oocyte donors' risks of infertility or cancer.
捐卵者在捐卵多年后提供的第一人称报告，可以提供有关捐卵医疗并发症的宝贵信息，以及美国体外受精 (IVF) 中心可能需要改变的程序和重点。本文报告了一项对前捐卵者进行在线调查的结果。
该工具是一个由作者构建的问卷，在捐卵者兄弟姐妹登记处网站上在线完成。问题评估了女性的医疗并发症经历、与提供卵子的不孕诊所的联系，以及与通过她们的卵子受孕的人的信息交流或联系。
收到了 287 名有有效电子邮件地址的捐卵者中的 49.1%的回复。155 名受访者平均在首次捐卵后 9.4 年完成了调查。报告的医疗并发症包括卵巢过度刺激综合征 (30.3%) 和不孕 (9.6%)。捐卵后，2.6%的女性报告说她们曾被 IVF 诊所联系以获取医疗更新。在问卷中，34.2%的女性报告说她们认为捐卵后发生的医疗变化可能会引起捐卵孩子的兴趣；一半人表示，她们曾试图向诊所报告这些变化，但结果不一。许多人没有报告这些信息，因为她们不知道自己可以或应该报告。捐卵者表示，由于对“匿名”或“保密”的定义感到困惑，她们经常没有寻求有关怀孕结果的信息。需要进行更多的长期研究，以确定卵子捐赠者不孕或癌症的风险。
