Witt Claudia M, Lüdtke Rainer, Willich Stefan N
Institute for Social Medicine, Epidemiology and Health Economics, Charité University Medical Center, Berlin, Germany.
Forsch Komplementmed. 2009 Aug;16(4):227-35. doi: 10.1159/000226770. Epub 2009 Jul 17.
Details and effects of individualised homeopathic treatment of headache (ICD-9: 784.0) in usual care have not yet been investigated.
Prospective multi-centre observational study. Consecutive primary-care patients beginning homeopathic treatment were followed for 2 years, keeping regular records of complaint severity, health-related quality of life (QoL), and medication use.
230 adults (77.0% women), age 38.2 +/- 11.3 years, and 74 children (10.4 +/- 3.2 years, 55.4% girls) treated by 73 physicians were included. Patients suffered from headaches (average duration: adults 9.3 +/- 9.5 years, children 2.7 +/- 2.6 years) and other chronic diseases. Most patients (adults 90.0%, children 70.8%) had been pre-treated (usually with conventional treatment). Severity of diagnoses and complaints showed marked improvements in the first 3 months, continuing on until the end of the study. For headache, standardised effects (mean change divided by standard deviation at baseline) in adults reached 1.63 (95% CI 1.78-1.49), 2.27 (2.45-2.09), and 2.44 (2.63-2.25) at 3, 12, and 24 months, respectively. In children, the standardised effects at these time points were 1.67 (1.91-1.44), 2.55 (2.82-2.28), and 2.74 (3.03-2.46), respectively. Whilst the QoL among adults improved over time, this trend was not observed in children. Use of conventional treatment and health services decreased markedly.
This observational study of patients seeking homeopathic treatment because of headache showed consistent improvements over the 24-month period. The observational and uncontrolled character of the study design does not allow conclusions on a specific relationship between treatment and the observed effects.
常规护理中个体化顺势疗法治疗头痛（国际疾病分类第九版：784.0）的细节和效果尚未得到研究。
前瞻性多中心观察性研究。对开始接受顺势疗法治疗的连续初级保健患者进行了2年的随访，定期记录症状严重程度、健康相关生活质量（QoL）和药物使用情况。
纳入了由73名医生治疗的230名成年人（77.0%为女性），年龄38.2±11.3岁，以及74名儿童（10.4±3.2岁，55.4%为女孩）。患者患有头痛（平均病程：成年人9.3±9.5年，儿童2.7±2.6年）和其他慢性病。大多数患者（成年人90.0%，儿童70.8%）曾接受过预处理（通常采用传统治疗）。诊断和症状的严重程度在最初3个月有显著改善，并持续到研究结束。对于头痛，成年人在3个月、12个月和24个月时的标准化效果（基线时的平均变化除以标准差）分别达到1.63（95%可信区间1.78 - 1.49）、2.27（2.45 - 2.09）和2.44（2.63 - 2.25）。在儿童中，这些时间点的标准化效果分别为1.67（1.91 - 1.44）、2.55（2.82 - 2.28）和2.74（3.03 - 2.46）。虽然成年人的生活质量随时间有所改善，但儿童中未观察到这种趋势。传统治疗和医疗服务的使用显著减少。
这项针对因头痛寻求顺势疗法治疗的患者的观察性研究表明，在24个月期间有持续改善。研究设计的观察性和非对照性特征不允许得出关于治疗与观察到的效果之间具体关系的结论。
