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慢性病中的人智学医学疗法:一项为期四年的前瞻性队列研究。

Anthroposophic medical therapy in chronic disease: a four-year prospective cohort study.

作者信息

Hamre Harald J, Witt Claudia M, Glockmann Anja, Ziegler Renatus, Willich Stefan N, Kiene Helmut

机构信息

Institute for Applied Epistemology and Medical Methodology, Freiburg, Germany.

出版信息

BMC Complement Altern Med. 2007 Apr 23;7:10. doi: 10.1186/1472-6882-7-10.

Abstract

BACKGROUND

The short consultation length in primary care is a source of concern, and the wish for more consultation time is a common reason for patients to seek complementary medicine. Physicians practicing anthroposophic medicine have prolonged consultations with their patients, taking an extended history, addressing constitutional, psychosocial, and biographic aspect of patients' illness, and selecting optimal therapy. In Germany, health benefit programs have included the reimbursement of this additional physician time. The purpose of this study was to describe clinical outcomes in patients with chronic diseases treated by anthroposophic physicians after an initial prolonged consultation.

METHODS

In conjunction with a health benefit program in Germany, 233 outpatients aged 1-74 years, treated by 72 anthroposophic physicians after a consultation of at least 30 min participated in a prospective cohort study. Main outcomes were disease severity (Disease and Symptom Scores, physicians' and patients' assessment on numerical rating scales 0-10) and quality of life (adults: SF-36, children aged 8-16: KINDL, children 1-7: KITA). Disease Score was documented after 0, 6 and 12 months, other outcomes after 0, 3, 6, 12, 18, 24, and (Symptom Score and SF-36) 48 months.

RESULTS

Most common indications were mental disorders (17.6% of patients; primarily depression and fatigue), respiratory diseases (15.5%), and musculoskeletal diseases (11.6%). Median disease duration at baseline was 3.0 years (interquartile range 0.5-9.8 years). The consultation leading to study enrolment lasted 30-60 min in 51.5% (120/233) of patients and > 60 min in 48.5%. During the following year, patients had a median of 3.0 (interquartile range 1.0-7.0) prolonged consultations with their anthroposophic physicians, 86.1% (167/194) of patients used anthroposophic medication. All outcomes except KITA Daily Life subscale and KINDL showed significant improvement between baseline and all subsequent follow-ups. Improvements from baseline to 12 months were: Disease Score from mean (standard deviation) 5.95 (1.74) to 2.31 (2.29) (p < 0.001), Symptom Score from 5.74 (1.81) to 3.04 (2.16) (p < 0.001), SF-36 Physical Component Summary from 44.01 (10.92) to 47.99 (10.43) (p < 0.001), SF-36 Mental Component Summary from 42.34 (11.98) to 46.84 (10.47) (p < 0.001), and KITA Psychosoma subscale from 62.23 (19.76) to 76.44 (13.62) (p = 0.001). All these improvements were maintained until the last follow-up. Improvements were similar in patients not using diagnosis-related adjunctive therapies within the first six study months.

CONCLUSION

Patients treated by anthroposophic physicians after an initial prolonged consultation had long-term reduction of chronic disease symptoms and improvement of quality of life. Although the pre-post design of the present study does not allow for conclusions about comparative effectiveness, study findings suggest that physician-provided anthroposophic therapy may play a beneficial role in the long-term care of patients with chronic diseases.

摘要

背景

基层医疗中咨询时间过短令人担忧,而希望获得更多咨询时间是患者寻求补充医学的常见原因。从事人智医学的医生与患者的咨询时间更长,会详细了解病史,关注患者疾病的体质、心理社会和传记方面,并选择最佳治疗方法。在德国,健康福利计划已将医生这部分额外时间的费用纳入报销范围。本研究的目的是描述在经过初始延长咨询后,由人智医学医生治疗的慢性病患者的临床结局。

方法

结合德国的一项健康福利计划,233名年龄在1 - 74岁的门诊患者参与了一项前瞻性队列研究,这些患者在经过至少30分钟的咨询后由72名人智医学医生进行治疗。主要结局指标为疾病严重程度(疾病和症状评分,医生和患者在0 - 10数字评分量表上的评估)和生活质量(成人:SF - 36,8 - 16岁儿童:KINDL,1 - 7岁儿童:KITA)。疾病评分在0、6和12个月时记录,其他结局指标在0、3、6、12、18、24个月以及(症状评分和SF - 36)48个月时记录。

结果

最常见的适应症为精神障碍(占患者的17.6%;主要是抑郁症和疲劳)、呼吸系统疾病(15.5%)和肌肉骨骼疾病(11.6%)。基线时疾病的中位持续时间为3.0年(四分位间距0.5 - 9.8年)。导致纳入研究的咨询时间在半数以上(51.5%,120/233)的患者中持续30 - 60分钟,48.5%的患者咨询时间超过60分钟。在接下来的一年中,患者与人智医学医生进行延长咨询的中位次数为3.0次(四分位间距1.0 - 7.0次),86.1%(167/194)的患者使用了人智医学药物。除KITA日常生活子量表和KINDL外,所有结局指标在基线与所有后续随访之间均显示出显著改善。从基线到12个月的改善情况如下:疾病评分从平均(标准差)5.95(1.74)降至2.31(2.29)(p < 0.001),症状评分从5.74(1.81)降至3.04(2.16)(p < 0.001),SF - 36身体成分总结评分从44.01(10.92)升至47.99(10.43)(p < 0.001),SF - 36心理成分总结评分从42.34(11.98)升至46.84(10.47)(p < 0.001),KITA身心子量表从62.23(19.76)升至76.44(13.62)(p = 0.001)。所有这些改善在最后一次随访时仍保持。在研究的前六个月内未使用与诊断相关辅助治疗的患者中,改善情况相似。

结论

经过初始延长咨询后由人智医学医生治疗的患者,慢性病症状长期减轻,生活质量得到改善。尽管本研究的前后设计无法得出关于相对有效性的结论,但研究结果表明,医生提供的人智医学疗法可能在慢性病患者的长期护理中发挥有益作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/57f0/1876246/2c625044228d/1472-6882-7-10-1.jpg

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