Department of Congenital Heart Disease, Evelina Children's Hospital, Guy's and St Thomas' NHS Foundation Trust, London, UK.
Ultrasound Obstet Gynecol. 2009 Oct;34(4):475-80. doi: 10.1002/uog.6433.
Ventricular tachycardia is a very rare fetal arrhythmia accounting for fewer than 2% of fetal tachycardias. We describe a fetus presenting at 30 weeks' gestation with ventricular tachycardia at a rate of 220 beats per min and fetal hydrops. The tachycardia was unresponsive to flecainide but was controlled within 12 h by an intravenous infusion of magnesium to the mother. Despite rapid control of the arrhythmia the fetus developed severe periventricular leukomalacia before birth for which a poor neurological prognosis was given. The baby was delivered preterm at 32 weeks' gestation and died on the sixth day after birth. Long QT syndrome was identified postnatally on the electrocardiogram, and was confirmed by genetic testing which showed a mutation in the KCNH2 gene (p.T613M).
室性心动过速是一种非常罕见的胎儿心律失常，占胎儿心动过速的比例不到 2%。我们描述了一例胎儿，在 30 孕周时出现 220 次/分的室性心动过速和胎儿水肿。该心动过速对氟卡尼无反应，但通过给母亲静脉输注镁，在 12 小时内得到控制。尽管心律失常得到迅速控制，但胎儿在出生前发展为严重的脑室周围白质软化，预后不良。婴儿在 32 孕周时早产，出生后第六天死亡。心电图检查发现新生儿存在长 QT 综合征，基因检测证实 KCNH2 基因（p.T613M）发生突变。
