O'Connor Mary J, Paley Blair
Department of Psychiatry and Biobehavioral Sciences, Semel Institute of Neuroscience and Human Behavior, David Geffen School of Medicine at UCLA, Los Angeles, California 90024, USA.
Dev Disabil Res Rev. 2009;15(3):225-34. doi: 10.1002/ddrr.74.
Since the identification of fetal alcohol syndrome (FAS) over 35 years ago, mounting evidence about the impact of maternal alcohol consumption during pregnancy has prompted increased attention to the link between prenatal alcohol exposure (PAE) and a constellation of developmental disabilities that are characterized by physical, cognitive, and behavioral impairments. These disabilities include a continuum of developmental disorders known as fetal alcohol spectrum disorders (FASDs). Longitudinal studies suggest that individuals with FASDs are at a greatly increased risk for adverse long-term outcomes, including mental health problems and poor social adjustment. This review summarizes the existing literature on mental health outcomes for individuals with PAE across the lifespan, including findings in infancy and early childhood, middle childhood, and adolescence and early adulthood. Research on the psychiatric disabilities suffered by individuals with FASDs throughout development highlights the need for training of mental health professionals in the identification and the provision of specific treatments to address the unique features of this developmental disability since early identification and treatment have been demonstrated to be protective against more serious secondary disabilities. It is hoped that with greater awareness of the mental health problems experienced by individuals with FASDs, these individuals can receive appropriate and early treatment resulting in more adaptive and rewarding lives.
自35多年前发现胎儿酒精综合征(FAS)以来,越来越多关于孕期母亲饮酒影响的证据促使人们更加关注产前酒精暴露(PAE)与一系列发育障碍之间的联系,这些发育障碍的特征是身体、认知和行为受损。这些障碍包括一系列被称为胎儿酒精谱系障碍(FASDs)的发育障碍。纵向研究表明,患有FASDs的个体出现不良长期后果的风险大大增加,包括心理健康问题和社会适应不良。本综述总结了关于PAE个体在整个生命周期中心理健康结果的现有文献,包括婴儿期和幼儿期、童年中期以及青少年期和成年早期的研究结果。对患有FASDs的个体在整个发育过程中所遭受的精神障碍的研究强调,需要对心理健康专业人员进行培训,以便识别并提供特定治疗,以应对这种发育障碍的独特特征,因为早期识别和治疗已被证明可以预防更严重的继发性障碍。希望随着对患有FASDs的个体所经历的心理健康问题有更多认识,这些个体能够得到适当的早期治疗,从而过上更具适应性和有意义的生活。