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Linkage and sequence conservation of the X-linked genes DXS253E (P3) and DXS254E (GdX) in mouse and man.

作者信息

Filippi M, Tribioli C, Toniolo D

机构信息

Istituto di Genetica Biochimica ed Evoluzionistica, CNR, Pavia, Italy.

出版信息

Genomics. 1990 Jul;7(3):453-7. doi: 10.1016/0888-7543(90)90184-v.

DOI:10.1016/0888-7543(90)90184-v
PMID:1973144
Abstract

Lambda G28, a mouse genomic clone homologous to the human P3 gene and associated with a CpG island, also hybridizes to human probes for the neighboring GdX gene. The two genes, P3 and GdX (DXS253E and DXS254E), physically linked on the human X chromosome, lie within a similar physical distance on the mouse X chromosome. The CpG island corresponds to that at the 5' of the human GdX gene. The relative orientation of the two genes is the same. The DNA sequence in coding and noncoding regions is very conserved.

摘要

相似文献

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