Department of Chemistry, Zhaoqing University, Zhaoqing, Guangdong 526061, P R China.
Chem Biodivers. 2010 Jan;7(1):229-35. doi: 10.1002/cbdv.200800349.
The composition of the essential oils obtained by hydrodistillation of different parts of Litsea cubeba, including roots, stems, leaves, alabastra (flower buds), flowers, and fruits, were investigated by GC (RI) and GC/MS. The antimicrobial activity of the oils was assessed with disc diffusion and microbroth dilution assays. The results showed large variations in the composition among the different oils. The major components in the oils from roots and fruits, from stems, leaves, and alabastra, and from flowers were citral B (neral), beta-phellandrene, and beta-terpinene, respectively. The inhibition zone (DD) and MIC values for the bacterial strains tested, which were all sensitive to the essential oil of L. cubeba, were in the range of 10.1-35.0 mm and 100-1000 microg/ml, respectively. Hence, the oils of the various parts showed moderate activity against the tested bacteria. This investigation showed that the antibacterial activity of L. cubeba was attributed to the essential oils, thus they can be a potential medicinal resource.
采用 GC（RI）和 GC/MS 对荜澄茄不同部位（根、茎、叶、花葶（花蕾）、花和果实）的水蒸气蒸馏精油的成分进行了研究。采用圆盘扩散和微量稀释法评估了油的抗菌活性。结果表明，不同油之间的成分存在很大差异。根和果实油、茎、叶和花葶油以及花油中的主要成分分别为柠檬醛 B（橙花醛）、β-蒎烯和β-萜品烯。所测试的细菌菌株对荜澄茄精油均敏感，其抑菌圈（DD）和 MIC 值范围分别为 10.1-35.0mm 和 100-1000μg/ml。因此，各部分的油对测试的细菌显示出中等活性。本研究表明，荜澄茄的抗菌活性归因于精油，因此它们可能是一种潜在的药用资源。
