Raslan H M Z, Ezzat W M, Abd El Hamid M F, Emam H, Amre K S
Department of Internal Medicine, National Research Centre, Cairo, Egypt.
East Mediterr Health J. 2009 May-Jun;15(3):692-700.
We assessed the dermatological manifestations associated with chronic hepatitis C virus (HCV) infection and their association with liver status. Of 155 patients with chronic HCV infection in Cairo, Egypt, 71 (45.8%) had dermatological manifestations: pruritus without evident skin lesions (21.3%), pigmented purpuric eruption (5.2%), aphthous ulcer and lichen planus (3.9% each), leukocytoclastic vasculitis (2.6%), psoriasis (1.9%), tinea versicolor (1.3%) and other conditions (5.8%). Shrunken liver, splenomegaly and ascites were significantly associated with the presence of skin lesions (relative risk 8.0, 2.7 and 1.8 respectively), and shrunken liver was significantly associated with pruritus (relative risk 2.1). Sex was not associated with any of the skin lesions.
我们评估了与慢性丙型肝炎病毒（HCV）感染相关的皮肤表现及其与肝脏状况的关联。在埃及开罗的155例慢性HCV感染患者中，71例（45.8%）有皮肤表现：无明显皮肤损害的瘙痒（21.3%）、色素性紫癜性皮疹（5.2%）、口腔溃疡和扁平苔藓（各3.9%）、白细胞破碎性血管炎（2.6%）、银屑病（1.9%）、花斑癣（1.3%）及其他情况（5.8%）。肝脏缩小、脾肿大和腹水与皮肤损害的存在显著相关（相对风险分别为8.0、2.7和1.8），肝脏缩小与瘙痒显著相关（相对风险2.1）。性别与任何皮肤损害均无关联。
