Sint Franciscus Gasthuis, GGZ Delfland, 3045 PM Rotterdam, The Netherlands.
Psychol Med. 2010 Jun;40(6):989-97. doi: 10.1017/S0033291709991012. Epub 2009 Sep 7.
In this study we compared subjects with obsessive and/or compulsive symptoms who did not meet all criteria for obsessive-compulsive disorder (OCD) (subthreshold subjects) to subjects with full-blown OCD and also to subjects without obsessions or compulsions.
The data were derived from the Netherlands Mental Health Survey and Incidence Study (NEMESIS), a large representative sample of the general Dutch population (n=7076). Using the Composite International Diagnostic Interview, Version 1.1 (CIDI 1.1), three groups were distinguished: subjects without lifetime obsessions or compulsions (94.2%), subthreshold subjects (4.9%) and subjects with full-blown OCD according to DSM-III-R (0.9%). These three groups were compared on various items, including psychological vulnerability, health and functional status, psychiatric co-morbidity and seeking treatment.
Subthreshold and OCD subjects had similar scores on the majority of the items measured. Thus, there was little difference between subthreshold and OCD subjects in health, functional status, psychological vulnerability and psychiatric co-morbidity. However, OCD and subthreshold subjects scored worse on most of these items when compared to the controls without obsessions or compulsions.
Having obsessions and compulsions is associated with substantial suffering and disability. Most subjects with obsessions and/or compulsions are not diagnosed with OCD according to the DSM-III-R criteria although these subjects generally display similar consequences to full-blown OCD subjects. We recommend that these subthreshold cases receive special attention in the development of DSM-V.
在本研究中,我们比较了未符合强迫症(OCD)所有诊断标准(阈下患者)的强迫症和/或强迫症状患者与确诊为 OCD 患者以及无强迫观念或强迫行为患者的差异。
该数据来源于荷兰精神健康调查与发病率研究(NEMESIS),这是一项针对荷兰普通人群的代表性大样本研究(n=7076)。采用复合国际诊断访谈问卷 1.1 版(CIDI 1.1),我们将研究对象分为三组:终生无强迫观念或强迫行为者(94.2%)、阈下患者(4.9%)和符合 DSM-III-R 标准的确诊 OCD 患者(0.9%)。我们比较了这三组在各种项目上的差异,包括心理脆弱性、健康和功能状态、共病精神障碍以及治疗寻求情况。
阈下患者和 OCD 患者在多数被测量项目上的评分相似。因此,阈下患者和 OCD 患者在健康、功能状态、心理脆弱性和共病精神障碍方面的差异较小。然而,与无强迫观念或强迫行为者相比,OCD 患者和阈下患者在这些项目的多数评分上均较差。
存在强迫观念和强迫行为与明显的痛苦和残疾相关。尽管这些患者通常表现出与确诊 OCD 患者相似的后果,但大多数存在强迫观念和/或强迫行为的患者并未根据 DSM-III-R 标准被诊断为 OCD。我们建议在 DSM-V 的制定中特别关注这些阈下病例。