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NeuroCog FX:癫痫患者认知功能的计算机化筛查

NeuroCog FX: computerized screening of cognitive functions in patients with epilepsy.

作者信息

Hoppe Christian, Fliessbach Klaus, Schlegel Uwe, Elger Christian E, Helmstaedter Christoph

机构信息

Department of Epileptology, University of Bonn Medical Centre, Sigmund-Freud-Strasse 25, 53105 Bonn, Germany.

出版信息

Epilepsy Behav. 2009 Oct;16(2):298-310. doi: 10.1016/j.yebeh.2009.07.041. Epub 2009 Sep 3.

DOI:10.1016/j.yebeh.2009.07.041
PMID:19733124
Abstract

NeuroCog FX, a computerized neuropsychological screening instrument for serial examinations of patients with epilepsy and other neurological diseases, was developed to fill the gap between unspecific ratings and comprehensive assessments. Eight subtests address attention, working memory, verbal and figural memory, and language. The test duration is less than 30min. In research contexts, the test can be applied at multiple sites by nonacademic personnel. Normative data were recorded from healthy subjects (N=244, age range=16-75years; retest: N=44; validation: N=40) and unselected patients from an epileptology unit (N=212; retest: N=94; validation: N=126). Psychometric analyses confirmed sufficient reliability and concurrent validity, particularly in patients. NeuroCog FX memory and overall performance scores showed "fair" to "good" diagnostic utility with respect to deficits revealed by established tests. NeuroCog FX provides reliable and valid measures of cognitive performance and may be used in clinical and research contexts as a screening instrument.

摘要

NeuroCog FX是一种用于对癫痫和其他神经疾病患者进行系列检查的计算机化神经心理学筛查工具,旨在填补非特异性评分与全面评估之间的空白。八个子测试涉及注意力、工作记忆、言语和图形记忆以及语言。测试时长不到30分钟。在研究环境中,非专业人员可在多个地点进行该测试。从健康受试者(N = 244,年龄范围 = 16 - 75岁;重测:N = 44;验证:N = 40)和癫痫科未经过挑选的患者(N = 212;重测:N = 94;验证:N = 126)中记录了常模数据。心理测量分析证实了足够的信度和同时效度,尤其是在患者中。NeuroCog FX的记忆和整体表现分数在已确立测试所揭示的缺陷方面显示出“尚可”到“良好”的诊断效用。NeuroCog FX提供了可靠且有效的认知表现测量方法,可在临床和研究环境中用作筛查工具。

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