Alrefai Ali, Habahbih Majed, Alkhawajah Mohammad, Darwish Mohammad, Batayha Waleed, Khader Yousef, El-Salem Khalid
Department of Neuroscience, Jordan University of Science and Technology, Irbid, Jordan.
Clin Neurol Neurosurg. 2009 Dec;111(10):812-5. doi: 10.1016/j.clineuro.2009.08.010. Epub 2009 Sep 5.
The prevalence of Parkinson's disease (PD) in Jordan is not known. This study describes the prevalence and clinical characteristics of PD in Northern Jordan.
Patients with the diagnosis of PD seen at neurology clinics in three major hospitals in Northern Jordan during the period of March 2007 to April 2008 were enrolled. PD diagnosis was established using predefined clinical diagnostic criteria.
A total of 102 patients were included in the analysis (64 males; 63%, 38 females 37%). The mean age (SD) of patients was 63.3 (10.1) years and the mean age for onset of symptoms (SD) was 59.5 (12.1) years. The crude prevalence rate of PD was estimated to be 59/100,000. Clinical presentations of PD at onset of disease included; rest tremor (79.2%), bradykinesia (28.7%), rigidity (6.9%), gait problem (5%), and postural instability (2%). Eleven patients (10.9%) had a family history of PD. There was no association between the age of symptom onset, the presence of tremor, bradykinesia, or rigidity at onset, with stage of PD measured by Hoehn and Yahr scale.
PD is a moderately prevalent disease in Jordan. The clinical characteristics of PD patients are similar to those reported in other countries.
约旦帕金森病（PD）的患病率尚不清楚。本研究描述了约旦北部PD的患病率及临床特征。
纳入2007年3月至2008年4月期间在约旦北部三家主要医院神经科门诊确诊为PD的患者。采用预先定义的临床诊断标准确立PD诊断。
共有102例患者纳入分析（64例男性，占63%；38例女性，占37%）。患者的平均年龄（标准差）为63.3（10.1）岁，症状出现的平均年龄（标准差）为59.5（12.1）岁。PD的粗患病率估计为59/100,000。疾病发作时PD的临床表现包括：静止性震颤（79.2%）、运动迟缓（28.7%）、肌强直（6.9%）、步态问题（5%）和姿势不稳（2%）。11例患者（10.9%）有PD家族史。症状出现的年龄、发病时震颤、运动迟缓或肌强直的存在与用Hoehn和Yahr量表测量的PD分期之间无关联。
PD在约旦是一种中度流行的疾病。PD患者的临床特征与其他国家报道的相似。
