Tong Yang, Wang Pingbao, Xia Zhaohua, Xia Xiaobo, Xu Xueliang
Department of Ophthalmology,Xiangya Hospital, Central South University, Changsha 410008, China.
Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2009 Aug;34(8):771-5.
To investigate the difference in color pattern reversal visual evoked potential (CPR-VEP)between primary open angle glaucoma (POAG) and primary angle closure glaucoma (PACG) patients.
Vision Monitor visual electrophysiograph made by Metro Vision Inc. in France was used to record CPR-VEP in 17 eyes of 12 POAG patients, 56 eyes of 41 PACG patients, and 26 eyes of 13 age-equivalent normal persons at an ascending series of temporal frequency (1, 2, 4, 8, 16, and 32 Hz) and color stimulation (black/white, red/green, and blue/yellow). P(100) wave amplitudes and latencies of these patients were compared respectively with those of the normal group.
With black/white stimulation, the P(100) wave amplitudes were reduced with the increase of temporal frequency in the 3 groups. The P(100) wave latencies were extended with the increase of temporal frequency with different color stimulations. The P(100) amplitudes were PACG group > NC group > POAG group and black/white > blue/yellow > red/green. The P(100) wave latencies in the POAG group and the PACG group were extended compared with the NC group, but there was no significant difference between PACG group and POAG group.
CPR-VEP P(100) amplitudes in the PACG group and POAG group have their own characteristics. The P(100) amplitude of PACG is higher, and POAG is lower than normal. The P(100) wave latencies of PACG and POAG are extended.
探讨原发性开角型青光眼(POAG)和原发性闭角型青光眼(PACG)患者之间颜色模式翻转视觉诱发电位(CPR-VEP)的差异。
使用法国Metro Vision公司生产的视觉监测视觉电生理仪,在12例POAG患者的17只眼中、41例PACG患者的56只眼中以及13例年龄匹配的正常人的26只眼中,以递增的时间频率系列(1、2、4、8、16和32Hz)和颜色刺激(黑/白、红/绿和蓝/黄)记录CPR-VEP。分别比较这些患者的P(100)波振幅和潜伏期与正常组的情况。
在黑/白刺激下,三组中P(100)波振幅均随时间频率增加而降低。不同颜色刺激下,P(100)波潜伏期随时间频率增加而延长。P(100)振幅为PACG组>正常对照组(NC组)>POAG组,且黑/白>蓝/黄>红/绿。POAG组和PACG组的P(100)波潜伏期与NC组相比延长,但PACG组和POAG组之间无显著差异。
PACG组和POAG组的CPR-VEP P(100)振幅有各自特点。PACG的P(100)振幅较高,POAG低于正常。PACG和POAG的P(100)波潜伏期延长。