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视觉诱发电位在原发性开角型青光眼视野缺损评估中的意义:综述

Significance of Visual Evoked Potentials in the Assessment of Visual Field Defects in Primary Open-Angle Glaucoma: A Review.

作者信息

Kothari Ruchi, Bokariya Pradeep, Singh Smita, Singh Ramji

机构信息

Department of Physiology, Mahatma Gandhi Institute of Medical Sciences, Sevagram, Wardha 442102, India.

Department of Anatomy, Mahatma Gandhi Institute of Medical Sciences, Sevagram, Wardha 442102, India.

出版信息

Neurosci J. 2013;2013:418320. doi: 10.1155/2013/418320. Epub 2012 Dec 6.

Abstract

Visual evoked potentials is an important visual electrophysiological tool which has been used for the evaluation of visual field defects in primary open-angle glaucoma and is an appropriate objective measure of optic nerve function. Significant correlations between the magnitude of the VEP parameters and MD of Humphrey static perimetry suggest that the impaired visual cortical responses observed in glaucoma patients can be revealed by both electrophysiological and psychophysical methods. In addition, the severity of global glaucomatous damage evidenced by reduction in MD could depend on the delay in neural conduction from retina to the visual cortex as revealed by the significant correlation between VEP latencies and MD which also supports the validity of the VEP testing in progression of glaucoma.

摘要

视觉诱发电位是一种重要的视觉电生理工具,已被用于评估原发性开角型青光眼的视野缺损,并且是视神经功能的一种合适的客观测量方法。视觉诱发电位参数的大小与 Humphrey 静态视野计的平均缺损(MD)之间存在显著相关性,这表明青光眼患者中观察到的视觉皮层反应受损可以通过电生理和心理物理学方法揭示。此外,平均缺损降低所证明的整体青光眼性损害的严重程度可能取决于从视网膜到视觉皮层的神经传导延迟,视觉诱发电位潜伏期与平均缺损之间的显著相关性揭示了这一点,这也支持了视觉诱发电位测试在青光眼进展中的有效性。

相似文献

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Impaired visual function in glaucoma.青光眼患者的视觉功能受损。
Clin Neurophysiol. 2001 Feb;112(2):351-8. doi: 10.1016/s1388-2457(00)00525-3.

本文引用的文献

5
EVOKED RESPONSE IN VISUAL DISORDERS.视觉障碍中的诱发电位
Ann N Y Acad Sci. 1964 May 8;112:305-19. doi: 10.1111/j.1749-6632.1964.tb26759.x.
9
Impaired visual function in glaucoma.青光眼患者的视觉功能受损。
Clin Neurophysiol. 2001 Feb;112(2):351-8. doi: 10.1016/s1388-2457(00)00525-3.

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