Gupta Nishant Kumar, Dixit Vinod Kumar
Department of Pharmaceutical Sciences, Natural Product Research Laboratory, Dr H.S. Gour University, Sagar, MP, India.
Nat Prod Res. 2009;23(14):1289-97. doi: 10.1080/14786410802447302.
Cleome viscosa Linn. (Family Capparidaceae) is naturalised throughout the hot and moist parts of India. Fresh leaves of this plant are used very effectively for the treatment of jaundice in the folk medicines of the Bundelkhand region of India. The hepatoprotective activity of the ethanolic extract of leaves was investigated against thioacetamide-induced hepatotoxicity in rats. The test material was found to be effectively hepatoprotective, as evidenced by biochemical parameters and histopathological studies. The hepatoprotective effect of ethanolic extract was comparable to that of silymarin, a standard hepatoprotective agent. The results of the present study support the traditional beliefs of the hepatoprotective effects of C. viscosa Linn.
白花菜（Cleome viscosa Linn.，山柑科）已在印度炎热潮湿的地区归化。在印度本德尔汗德地区的民间药物中，这种植物的新鲜叶子被非常有效地用于治疗黄疸。研究了该植物叶子乙醇提取物对硫代乙酰胺诱导的大鼠肝毒性的保肝活性。生化参数和组织病理学研究表明，受试材料具有有效的保肝作用。乙醇提取物的保肝作用与标准保肝剂水飞蓟素相当。本研究结果支持了白花菜具有保肝作用的传统观点。
