Department of Pathology, Shri B. M. Patil Medical College and Research Centre, Bijapur, India.
Indian J Dermatol Venereol Leprol. 2009 Sep-Oct;75(5):506-8. doi: 10.4103/0378-6323.55397.
Trichoblastoma is a rare benign trichogenic tumour with epithelial and mesenchymal components recapitulating the germinal hair bulb and associated mesenchyme. A 50- year- old male patient presented with slowly enlarging circumscribed solid nodule measuring 4x3x4.5 cm over the tip of the nose. Microscopy of tumour revealed nodular tumour spanning the entire dermis with collection of mesenchymal cells resembling follicular papilla. Areas of pigmentation and sebaceous hyperplasia were noted. There is a need for differentiation of this tumor which is benign, from other pigmented tumors having basaloid arrangement of cells such as basal cell carcinoma.
毛母细胞瘤是一种罕见的良性毛源性肿瘤，具有上皮和间充质成分，重现生发毛囊和相关间充质。一名 50 岁男性患者出现鼻尖逐渐增大的界限清楚的实性结节，大小为 4x3x4.5cm。肿瘤显微镜检查显示整个真皮层有结节状肿瘤，有类似于毛囊乳头的间质细胞聚集。注意到有色素沉着和皮脂腺增生区域。需要将这种良性肿瘤与具有基底样细胞排列的其他色素性肿瘤（如基底细胞癌）区分开来。
