Requena L, Requena I, Romero E, Sánchez M, Sánchez Yus E
Departamento de Dermatología, Hospital Clínico de San Carlos, Facultad de Medicina, Universidad Complutense, Madrid, Spain.
Am J Dermatopathol. 1990 Apr;12(2):175-81.
Tumors of hair germ are a very rare group of primary cutaneous neoplasms that have been divided into two groups: epithelial and mesenchymal. Epithelial neoplasms of hair germ are further subdivided into those that are purely epithelial (trichoblastomas) and into epithelial neoplasms with mesenchymal components that may cause inductive changes toward the earliest phase of hair follicle differentiation (trichoblastic fibroma) or a more advanced and complete hair follicle formation (trichogenic trichoblastoma). We herein report an ulcerated trichogenic trichoblastoma whose epithelial and mesenchymal components recapitulated the formation of numerous primitive dermal papillae of the hair bulb because there were numerous strands of small polygonal epithelial cells that delimited areas of a dense and abundantly cellular connective tissue in a hair papilla-like pattern.
毛母质瘤是一组非常罕见的原发性皮肤肿瘤,可分为两组:上皮性和间叶性。毛母质上皮性肿瘤进一步细分为纯上皮性肿瘤(成毛细胞瘤)和具有间叶成分的上皮性肿瘤,后者可导致向毛囊分化最早阶段的诱导性改变(毛母质纤维瘤)或更高级和完整的毛囊形成(生毛成毛细胞瘤)。我们在此报告一例溃疡性生毛成毛细胞瘤,其上皮和间叶成分重现了毛球中众多原始毛乳头的形成,因为有许多小多边形上皮细胞束,以毛乳头样模式界定了致密且细胞丰富的结缔组织区域。