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通过克隆和测序鉴定的HLA - Cw*030301基因组全长序列。

Genomic full length sequence of HLA-Cw*030301, identified by cloning and sequencing.

作者信息

Xu Y, Deng Z, Zeng J, Gao S, Yang B

机构信息

Key Laboratory of Shenzhen for Histocompatibility and Immunogenetics, Shenzhen Blood Center, Shenzhen, PR China.

出版信息

Tissue Antigens. 2009 Nov;74(5):452-3. doi: 10.1111/j.1399-0039.2009.01352.x. Epub 2009 Sep 18.

DOI:10.1111/j.1399-0039.2009.01352.x
PMID:19765259
Abstract

Genomic full length sequence of human leukocyte antigen (HLA)-Cw030301 that differs from Cw030401 by two-nucleotide exchange at nt 473 (G>A) in exon 2 and nt 3033 (G>C) in 3'UTR, was identified by cloning and sequencing from a male Chinese donor.

摘要

通过对一名中国男性供体进行克隆和测序,鉴定出人类白细胞抗原(HLA)-Cw030301的基因组全长序列,该序列与Cw030401的区别在于,第2外显子的第473位核苷酸(G>A)和3'非翻译区的第3033位核苷酸(G>C)发生了两个核苷酸的交换。

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