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虹膜切开术后眼压持续升高的原发性闭角型青光眼的选择性激光小梁成形术

Selective laser trabeculoplasty for primary angle closure with persistently elevated intraocular pressure after iridotomy.

作者信息

Ho Ching Lin, Lai Jimmy S M, Aquino Mario V, Rojanapongpun Prin, Wong Hon Tym, Aquino Ma Cecilia, Gerber Yariv, Belkin Michael, Barkana Yaniv

机构信息

Department of Ophthalmology, Singapore National Eye Center, Tan Tock Seng Hospital, Singapore.

出版信息

J Glaucoma. 2009 Sep;18(7):563-6. doi: 10.1097/IJG.0b013e318193c2d1.

Abstract

PURPOSE

To determine whether selective laser trabeculoplasty (SLT) can lower intraocular pressure (IOP) in eyes with chronic primary angle closure, elevated IOP, and a patent iridotomy.

PATIENTS AND METHODS

Patients with chronic angle closure who had underwent iridotomy, had an IOP greater than 21 mm Hg and a gonioscopically visible pigmented trabecular meshwork for at least 90 degrees were enrolled. SLT was applied to open angle segments. Duration of follow-up was 6 months.

RESULTS

Sixty eyes of 60 patients were enrolled. The mean baseline IOP was 24.6+/-2.5 mm Hg. At 6 months, IOP reduction of > or =3 mm Hg or 4 mm Hg was measured in 82% and 72% of eyes, respectively, and IOP reduction of > or =20% or 30% was measured in 54% and 24% of eyes, respectively. When only eyes that were treated with the same number or fewer medications were considered, these IOP reductions were measured in 67%, 58%, 43%, and 15%, respectively. During the study period 1 eye (1.7%) required trabeculectomy owing to IOP elevation shortly after the SLT. There were no other significant complications attributable to SLT.

CONCLUSIONS

SLT seems to be a safe and effective method of reducing IOP in many eyes with primary angle closure and a patent iridotomy in which there is a sufficient extent of visible trabecular meshwork.

摘要

目的

确定选择性激光小梁成形术(SLT)能否降低慢性原发性闭角型青光眼、眼压升高且虹膜周切术通畅患者的眼压。

患者与方法

纳入慢性闭角型青光眼患者,这些患者已接受虹膜周切术,眼压大于21mmHg,房角镜下可见色素性小梁网至少90度。对开角象限进行SLT治疗。随访时间为6个月。

结果

纳入60例患者的60只眼。平均基线眼压为24.6±2.5mmHg。6个月时,分别有82%和72%的眼眼压降低≥3mmHg或4mmHg,分别有54%和24%的眼眼压降低≥20%或30%。仅考虑使用相同数量或更少药物治疗的眼时,这些眼压降低率分别为67%、58%、43%和15%。在研究期间,1只眼(1.7%)因SLT后不久眼压升高而需要行小梁切除术。没有其他可归因于SLT的严重并发症。

结论

对于许多原发性闭角型青光眼且虹膜周切术通畅、可见小梁网范围足够的眼,SLT似乎是一种安全有效的降低眼压方法。

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