Ho Ching Lin, Lai Jimmy S M, Aquino Mario V, Rojanapongpun Prin, Wong Hon Tym, Aquino Ma Cecilia, Gerber Yariv, Belkin Michael, Barkana Yaniv
Department of Ophthalmology, Singapore National Eye Center, Tan Tock Seng Hospital, Singapore.
J Glaucoma. 2009 Sep;18(7):563-6. doi: 10.1097/IJG.0b013e318193c2d1.
To determine whether selective laser trabeculoplasty (SLT) can lower intraocular pressure (IOP) in eyes with chronic primary angle closure, elevated IOP, and a patent iridotomy.
Patients with chronic angle closure who had underwent iridotomy, had an IOP greater than 21 mm Hg and a gonioscopically visible pigmented trabecular meshwork for at least 90 degrees were enrolled. SLT was applied to open angle segments. Duration of follow-up was 6 months.
Sixty eyes of 60 patients were enrolled. The mean baseline IOP was 24.6+/-2.5 mm Hg. At 6 months, IOP reduction of > or =3 mm Hg or 4 mm Hg was measured in 82% and 72% of eyes, respectively, and IOP reduction of > or =20% or 30% was measured in 54% and 24% of eyes, respectively. When only eyes that were treated with the same number or fewer medications were considered, these IOP reductions were measured in 67%, 58%, 43%, and 15%, respectively. During the study period 1 eye (1.7%) required trabeculectomy owing to IOP elevation shortly after the SLT. There were no other significant complications attributable to SLT.
SLT seems to be a safe and effective method of reducing IOP in many eyes with primary angle closure and a patent iridotomy in which there is a sufficient extent of visible trabecular meshwork.
确定选择性激光小梁成形术(SLT)能否降低慢性原发性闭角型青光眼、眼压升高且虹膜周切术通畅患者的眼压。
纳入慢性闭角型青光眼患者,这些患者已接受虹膜周切术,眼压大于21mmHg,房角镜下可见色素性小梁网至少90度。对开角象限进行SLT治疗。随访时间为6个月。
纳入60例患者的60只眼。平均基线眼压为24.6±2.5mmHg。6个月时,分别有82%和72%的眼眼压降低≥3mmHg或4mmHg,分别有54%和24%的眼眼压降低≥20%或30%。仅考虑使用相同数量或更少药物治疗的眼时,这些眼压降低率分别为67%、58%、43%和15%。在研究期间,1只眼(1.7%)因SLT后不久眼压升高而需要行小梁切除术。没有其他可归因于SLT的严重并发症。
对于许多原发性闭角型青光眼且虹膜周切术通畅、可见小梁网范围足够的眼,SLT似乎是一种安全有效的降低眼压方法。