Rowe-Jones J M, Macallan D C, Sorooshian M
Department of Otolaryngology, St George's Hospital, London.
J Laryngol Otol. 1990 Jul;104(7):562-4. doi: 10.1017/s0022215100113179.
Sudden onset sensorineural hearing loss is an otological emergency. Although deafness is recognised as being associated with polyarteritis nodosa (PAN) only very rarely does it herald the disease. We describe a case of bilateral, sudden onset vestibulo-cochlear failure which with thorough investigation proved to be the presenting complaint of PAN. This diagnosis enabled definitive management of a multi-system disorder and resulted in an improvement of the initial symptom with the chemotherapeutic regime discussed. We review the involvement of PAN in deafness and hope this case will remind otolaryngologists of the need for full investigation of the above mentioned emergency, in an attempt to discover and hence direct management towards a specific underlying pathology.
突发性感音神经性听力损失是一种耳科急症。虽然耳聋仅在极罕见的情况下被认为与结节性多动脉炎（PAN）相关，但它很少是该疾病的先兆。我们描述了一例双侧突发性前庭蜗神经功能衰竭病例，经过全面检查，证实这是PAN的首发症状。这一诊断使得对这种多系统疾病能够进行明确的治疗，并通过所讨论的化疗方案使初始症状得到改善。我们回顾了PAN与耳聋的关系，希望这个病例能提醒耳鼻喉科医生，对于上述急症需要进行全面检查，以便发现并针对特定的潜在病理进行治疗。
