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8-甲氧基补骨脂素处理后，植物血凝素（PHA）刺激的人白细胞增殖增加。

Increased proliferation of phytohaemagglutinin (PHA)-stimulated human leucocytes after 8-methoxypsoralen treatment.

作者信息

Gawron A, Górski G, Głowniak K

机构信息

Department of Cell Biology, M. Curie-Skłodowska University, Lublin, Poland.

出版信息

J Pharm Pharmacol. 1990 Mar;42(3):194-5. doi: 10.1111/j.2042-7158.1990.tb05384.x.

DOI:10.1111/j.2042-7158.1990.tb05384.x
PMID:1974616
Abstract

The effect of 8-methoxypsoralen on human blood mononuclear cells cultured in darkness has been examined. 8-Methoxypsoralen (1 microgram mL-1, 4.6 microM) added to (phytohaemagglutinin-stimulated cells induced a two-fold increase in the number of mitoses. The number of blastic cells also increased. There was no effect on the formation of micronuclei and there was no chromosomal breakage.

摘要

已对8-甲氧基补骨脂素在黑暗中培养的人血单核细胞上的作用进行了研究。添加到（植物血凝素刺激的细胞）中的8-甲氧基补骨脂素（1微克/毫升，4.6微摩尔）使有丝分裂数增加了两倍。母细胞数量也增加了。对微核形成没有影响，也没有染色体断裂。

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