Linaker O M
Department of Psychiatry and Behavioural Medicine, University of Trondheim, Norway.
Br J Psychiatry. 1990 Apr;156:525-30. doi: 10.1192/bjp.156.4.525.
The frequency of psychotropic and anticonvulsant drug use in 168 institutionalised mentally retarded adults was studied. Use of neuroleptics and anticonvulsants was more frequent and use of hypnotics and antidepressants less frequent than in the general population. Neuroleptics were given to 49% of the population. Clients with no psychiatric diagnosis consumed less neuroleptics than those with such a diagnosis, and there was a non-significant trend for those with a more serious diagnosis (e.g. schizophrenia) to take a higher dosage. The degree of disruptive behaviour and the availability of a physician were related to dosage of neuroleptics. The various psychiatric diagnoses given could explain only a small proportion of the variance in dosage.
对168名机构收容的成年智障者使用精神药物和抗惊厥药物的频率进行了研究。与普通人群相比，使用抗精神病药物和抗惊厥药物的频率更高，而使用催眠药和抗抑郁药的频率更低。49%的人使用了抗精神病药物。没有精神疾病诊断的患者服用的抗精神病药物比有此类诊断的患者少，并且诊断更严重（如精神分裂症）的患者服用更高剂量的药物存在不显著的趋势。破坏性行为的程度和医生的可及性与抗精神病药物的剂量有关。给出的各种精神疾病诊断只能解释剂量差异的一小部分。
