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抗精神病药物、学习障碍与社区:一些历史与谜团

Neuroleptics, learning disability, and the community: some history and mystery.

作者信息

Manchester D

机构信息

York Clinical Psychology Services, Clifton Hospital.

出版信息

BMJ. 1993 Jul 17;307(6897):184-7. doi: 10.1136/bmj.307.6897.184.

Abstract

Recent papers have again highlighted the consistently high use of neuroleptic agents among people with a learning disability, despite the lack of good evidence to support their role in this population for behaviour management and despite the risks of such medication. Evidence suggests, however, that prescribing habits have remained relatively unchanged; the reasons for this are poorly understood. Given the lack of understanding about the factors contributing to such drug use, and the possibility that use of neuroleptics will increase as people with learning disabilities move into the community, there seems a clear need for clinical guidelines to cover the prescribing and monitoring of neuroleptics within this group. Such guidelines should also ensure that reviews, using reliable measures of treatment efficacy, are carried out regularly.

摘要

近期的论文再次强调,尽管缺乏充分证据支持在学习障碍人群中使用抗精神病药物进行行为管理,且这类药物存在风险,但该类药物在这一人群中的使用一直居高不下。然而,有证据表明,处方习惯相对没有变化;对此原因了解甚少。鉴于对导致此类药物使用的因素缺乏了解,且随着学习障碍患者进入社区,抗精神病药物的使用可能会增加,显然需要临床指南来指导该群体抗精神病药物的处方和监测。此类指南还应确保定期使用可靠的治疗疗效衡量指标进行评估。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a155/1678355/231437b32b94/bmj00030-0047-a.jpg

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